Báo cáo khoa học: "The radioprotective effects of the hexane and ethyl acetate extracts of Callophyllis japonica in mice that undergo whole body irradiation" pps
Báo cáo khoa học: Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor ppt
... position of the intact His-tagged H1 receptor is indicated by the arrow. The quantity of the remaining minor contaminating bands in the purified receptor variedbetween preparations. Their identity ... structure and receptor–ligandinteractions of the histamine receptors. Elucidation of the structure and dynamics of membrane proteins is a challen-ging task essential for proper understanding of the ... [28]. The N-terminal sequence of the H1 receptor indeed containstwo N-linked glycosylation consensus sites, but in prelim-inary studies no binding to concanavalin A was observed,indicating that...
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Tài liệu Báo cáo khoa học: Secondary substrate binding strongly affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases docx
... Because the activity on X6remains the sameupon engineering of the SBS of XBS, the resultsobtained in the previous screening experiment directlyTable 1. The effect of genetic engineering of the ... obtained in the present study, it might be speculated that SBS isinvolved in targeting the enzymes towards their sub-strate and, subsequently, in anchoring them onto the substrate or in feeding ... compensate for their lack of CBMs.Results and DiscussionGenetic engineering of the SBSResidues of the SBS of both XBS and XAN involved in substrate interaction were selected based on the crystal...
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Báo cáo khoa học: Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing docx
... pipette tip and incubatedfor 24 h. Data are the mean ± SD of the distance that leading edge of the monolayertraveled into the wound area in fiverandomly selected fields from threeindependent ... protein that mediates integrin sig-naling leading to cell migration, in cell polarization. In the present study, we found that Cas was essential for the polarization of migrating cells. Scratch-inducedelongation ... and stained for GM130 to visualize the Golgi.Cells on the wound edge were divided equally into threesectors, including the front sector between the nucleus and the leading edge. The Golgi in...
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Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx
... xtent of structure formationwithin the main a-helix (residues 24–33), and examine the integrity o f the helix C-capping motif and of the s hort helix(residues 3 8–40). In ubiquitin, the C-capping ... to the side chains of Lys27 and Gln31 in the main a-helix are also evident and confirm t hat the Ala38 methyl g roup occupies the samehydrophobic pocket as the side chain of Pro38. Mod elling the ... 4483protein stability, and their involvement in the foldingpathway from studies of refolding/unfolding kinetics. While the single point mutation P37A is destabilizing b y4.5 kJÆmol)1, in contrast...
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Báo cáo khoa học nông nghiệp " Effects of Stocking Biomass on Growth, Survival and Production of the Two Sizes of Clam Meretrix lyrata Cultured in the Intertidal Areas And Notes on Hatchery Production of Clam Spat " pot
... of the clam was significant increased as increasing of stocking biomass (p<0.05). The percentage of biomass gained, in contrast, was reduced as increasing of stocking biomass in T5, T6 and ... difference (p>0.05) in the biomass gained in the treatment T5 and T6 nor percentage of biomass gained in the treatments T7 and T8. In both size groups, the increase in biomass certainly impacted ... showed in the table 7. The net profit calculated base on the output cost and input cost and price of the clam. The main cost in M. lyrata cultivation was the expense in seed purchase. Cost of seed...
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Báo cáo khoa học: " Dose-Incidence Relationships on the Prenatal Effects of Gamma-Radiation in Mice" pdf
... length was measured from the tip of the snouttothebaseofthetail.Thelongitudinaldistancefromthetipofthesnouttothebaseoftheskullwasrecordedas head length. The distance between the two ears wasrecorded ... the organs undergoingdifferentiation at the time of the irradiation, the stage of differentiation and the radiation dose [1]. The effect of irradiation during the early period of murinedevelopment, ... dilatation of cerebral ventricle and abnormalities of the extremities in live fetusesrose. The threshold doses of radiation that inducedcleft palate and dilatation of cerebral ventricle, and abnormal...
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Tài liệu Báo cáo khoa học: Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft doc
... withchagasin and stefin A shows that the magnitude of the shift of the occlud-ing loop is related to the size of the binding region. It is smallest in the procathepsin structures and increases in the ... features of the ligands that competewith the occluding loop for binding to the active site, the farther away the occluding loop residues areshifted. As seen in the tetragonal form of the cathepsinB ... and the different enzymes is the averagedistance between the centre of mass of CA atoms of the stefin molecule and the centre of mass of the CA atoms of the reactive site cysteine and histidine...
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Tài liệu Báo cáo khoa học: Branched N-glycans regulate the biological functions of integrins and cadherins doc
... the regulation of integrin function. Therefore, we speculate that modifi-cation of particular sites, which are involved in regula-tion of the conformation of integrin, determine the extent of ... suppressedby the upregulation of GnT-III. In fact, the results of several studies suggest that E-cadherin can induceligand-independent activation of EGFR and subse-quent activation of Rac1 and MAP kinase, ... mayexplain why bisecting GlcNAc-containing N-glycansare abundant in the brain [65]. In fact, mice carryingan inactive GnT-III mutant have an atypical neurolog-ical phenotype [66]. The data obtained...
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Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modifications ppt
... acute and chronic in ammation in mammalian brain tissue both in vitro and in vivo,including in the detection of cerebral malaria.Retooling of this reporter system also allowed sys-tematic investigation ... suggests that neu-rons display selective GlcNAc-binding proteins, anintriguing result in the light of previous work on the proposed role of GlcNAc regarding both the nuclearlocalization of Alzheimer’s-associated ... control of their biosynthesis, natural PTMs vary in site and level of incorporation, leading to mixtures of modified pro-teins that may differ in function. In order to fully dis-sect the biological...
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Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx
... suggested the unwinding of the single a-helix at the C-terminal portion of c, thus allowingfor unimpaired rotation of the remainder of c.Furthermore, the calculations suggested the very end of c ... revealed the possibility of a‘functional unwinding’ of the a-helix to form a swivel joint.Furthermore, they suggested a firm clamping of that part of c even without the engineered cross-link, i.e. in ... were incor-porated into the two noncross-linked positions of subunit a of the oxidized mutant MM10 (Fig. 2). After reduction of the nonfluorescent cross-linked ac the effects of ligandbinding and...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ