Báo cáo khoa học: "pH-dependent modulation of intracellular free magnesium ions with ion- selective electrodes in papillary muscle of guinea pig" ppt
Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... inhibition) and was comparable to thatobtained upon tethering of TTP to the same reportermRNA. These results indicate that ASF ⁄ SF2 is apotent repressing factor in the absence of competingfactors. ... 2497 ASF/SF2 down-regulates the expression of areporter luciferase mRNA when tethered to the 3Â UTR The function of ASF SF2 in mRNA metabolism wasfurther analyzed by a tethering approach. This ... considered to regulate the stability and ⁄ ortraductibility of 8% of all human mRNAs [2]. RNA-binding proteins comprise other key components of the post-transcriptional regulation of gene expression. These...
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Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt
... subfamilyand, in this case, even to a subset of eight members. The finding that, within the A-6 subfamily, not all of its members interact with BPM1 indicates that BPM proteins assemble only with ... proteins assemble with members of the ERF⁄AP2 transcription factor family Because it has been shown previously that Arabidopsis BPM proteins use their BTB ⁄ POZ domain to interact with the cullins ... to assemble with members of the ethylene response factor ⁄ Apetala2 (ERF ⁄ AP2) tran-scription factor family. We also provide a detaileddescription of the Arabidopsis thaliana BPM family expression...
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Tài liệu Báo cáo khoa học: Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin Optical and NMR spectroscopy characterization pptx
... °C. Myristate and Mn(III)heme binding to HSA–heme G. Fanali et al .4678 FEBS Journal 272 (2005) 4672–4683 ª 2005 FEBS Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin Optical ... albu-min conformation on the binding of warfarin to human serum albumin. The dependence of the binding of war-farin to human serum albumin on the hydrogen, cal-cium, and chloride ion concentrations ... transition, and appear of generalsignificance for a deeper understanding of the allosteric modulation of ligand binding properties of HSA.AbbreviationsFA, fatty acid; HSA, human serum albumin; ...
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Báo cáo khoa học: Dual modulation of prothrombin activation by the cyclopentapeptide plactin pptx
... the N-terminus of itsB-chain [19]. The sequential mechanism leading toenhancement of scu-PA activation is shown in Fig. 3F. Dual modulation of prothrombin activation by plactin The above results ... (Fig. 4). These properties of the plactin prothrombin interaction suggested a change in the conformation of prothrombin after plactin bind-ing. We measured the intrinsic fluorescence of prothrombin ... even under theseconditions (Fig. 6B). Therefore, it was likely that plactin prothrombin binding altered the conformation of prothrombin and resulted in dual modulation of prothrombin activation, ...
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Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx
... MINIREVIEW The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease Peter J. Crouch1, Anthony R. White1and Ashley I. Bush2,31 Department of Pathology ... bio-availability have the potential to ameliorate several of the dysfunctional events characteristic of Alzheimer’s disease. Metal- basedtherapeutics have already provided promising results for the ... because of animbalance in the activity of tau kinases and phospha-tases [3]. One particular tau kinase pertinent to metal dyshomeostasis in AD is glycogen synthase kinase-3(GSK3). GSK3 has...
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Báo cáo khoa học: "The Modulation of Cooperation and Emotion in Dialogue: The REC Corpus" pdf
... (the giver) must drive the other participant (the follower) from a starting point (the bus station) to the finish (the Castle). Figure 1: Maps used in the recording of REC corpus Giver and ... 81–87,Suntec, Singapore, 4 August 2009.c2009 ACL and AFNLP The Modulation of Cooperation and Emotion in Dialogue: The REC Corpus Federica Cavicchio Mind and Brain Center/ Corso Bettini 31, 38068 ... One of the main open issues is the annotation of the so-called “blended” emotions and their recognition. Usually, there is a low agreement among raters in annotating emotions and, surprisingly,...
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Báo cáo khoa học: Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA docx
... efficient cleavage of 35S pre-rRNA at sites A 0 ,A 1 and A 2. Depletion of Utp25p causes the accumulation of the pre-rRNA 35S and the aberrant 23S, a consequent decrease in the lev-els of mature 18S ... that upon depletion of Utp25p there is anaccumulation of the pre-rRNA 35S and the aberrant23S, and a decrease in pre-rRNA 20S and mature 18SrRNA (Fig. 5A) . The large ribosomal subunit RNAs25S, ... Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA Mauricio B. Goldfeder and Carla C. OliveiraDepartment of Biochemistry,...
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Báo cáo khoa học: C-terminal truncated cannabinoid receptor 1 coexpressed with G protein trimer in Sf9 cells exists in a precoupled state and shows constitutive activity ppt
... show that at least thedistal C-terminal tail ( 418 –472) is not involved in CB1( 417 ) G +G Anti-Flag M2 IgGAnti-His tag IgGAnti-His tag IgGAnti -G i1 /G i2IgG Receptor Receptor G Gi1Fig. 7. ... was 5Â-GC G GAT CC G ACC ATGGCG AAG TCG ATC CTA GAT GGC-3Â. The reverseprimer for the full-length CB1 gene, with EcoRI and NotIrestriction sites, was 5Â-GAA T GC GGC CGC TCA CTTTTC GAA TTG ... from Sigma-Aldrich Chemie GmbH(Munich, Germany). Anti-Gai1⁄ Gai2IgG was purchasedfrom Calbiochem (Merck KGaA, Darmstadt, Germany).Anti-flag M2 IgG agarose was obtained from Sigma-Aldrich...
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Báo cáo khoa học: Allosteric modulation of Euphorbia peroxidase by nickel ions pdf
... lost.The effect of Ni2+in the absence of added CaCl2was determined by inverse plots of the steady-statekinetics at saturating concentrations of ABTS (10 mm) Nickel ions and Euphorbia peroxidase ... (2008) 12011212 ê 2008 The Authors Journal compilation ê 2008 FEBS Allosteric modulation of Euphorbia peroxidase by nickel ions Francesca Pintus1, Anna Mura1, Andrea Bellelli2, Alessandro ... catalyticpathways of native Euphorbia latex peroxidase (ELP)and in the presence of Ca2+. The enzyme is stronglyinhibited by Ni2+in the absence of Ca2+, whereas,in the presence of both Ca2+and...
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Báo cáo khoa học: "A biologically competitive 21 days hypofractionation scheme with weekly concomitant boost in breast cancer radiotherapy feasibility acute sub-acute and short term late effects" pot
... AccessA biologically competitive 21 days hypofractionation scheme with weekly concomitant boost in breast cancer radiotherapy feasibility acute sub -acute and short term late effectsMarina Guenzi1†, ... Guenzi et al.: A biologically competitive 21 days hypofractionation scheme with w eekly concomitant boost in breast cancer radiotherapy feasibility acute sub -acute and short term late effects.Radiation ... acceleratedhypofractionated schedule in terms of acute, subacute and short- term late toxicity. This useful 13 fractions with a concomitant boost schedule seems, in selected patients, a biologically acceptable...
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Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
... report Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung CancerApollonia LJ Uitterhoeve*1, ... days) combined with either concomitant daily low dose cisplatin or with two neo-adjuvant courses of gemcitabin and cisplatin areeffective treatments for patients with locally advanced Non-Small Cell ... Kroonenburgh M, OllersM, Lambin P: Effects of radiotherapy planning with a dedicated combined PET-CT-simulator of patients with non-small cell lung cancer on dose limiting normal tissues and radiationdose-escalation:...
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báo cáo khoa học: " Barriers to research utilization and research use among registered nurses working in the care of older people: Does the BARRIERS Scale discriminate between research users and non-research users on perceptions of barriers?" pptx
... per-ceptions of barriers to, and facilitators of, research utiliza-tion and to examine the validity of the BARRIERS scale in relation to research use, i.e., the capacity of the Scale to discriminate ... to examine the validity of the BARRIERS scale in relation to research use, i.e., assess the BARRIERS scale& apos;s capacity to discriminate perceptions of barriers between research users and non -research ... to research utilization between research users and non- research users on the Nurse, the Research and the Presen-tation subscales, indicating that the instrument appearsuseful for identifying...
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báo cáo khoa học: " Can patient decision aids help people make good decisions about participating in clinical trials? A study protocol" pptx
... decision aids help people make good decisions about participating in clinical trials? A study protocolJamie C Brehaut*1,2, Alison Lott5, Dean A Fergusson1,2, Kaveh G Shojania6, Jonathan ... in clinical trials can be inadequate, with study participants frequently not understanding even basicinformation fundamental to giving informed consent. Patient decision aids are effective decision support ... Jonathan Kimmelman4 and Raphael Saginur1,3Address: 1Ottawa Health Research Institute, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, Ontario, K1Y 4E9, Canada, 2Department of Epidemiology...
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Báo cáo khoa học: "Medical post-traumatic stress disorder: catching up with the cutting edge in stress research" ppt
... the threshold value of 35, even though their symptoms were notCommentaryMedical post-traumatic stress disorder: catching up with the cutting edge in stress researchCraig Weinert1and William Meller21Pulmonary, ... diagnosis of post-traumatic stress disorder (PTSD) and discuss the use ofcontinuous measures of PTSD in comparison with diagnosticinstruments. Problems with distinguishing incident from prevalentPTSD ... of‘screening’ instruments rather than ‘diagnostic’ PTSDinstruments or interviews? In the formal definition of PTSD in DSM-IV [5], this disorder is diagnosed when there are aminimum number of...
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Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíChuong 2 nhận dạng rui roQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ