Báo cáo khoa học: "The anti-thrombotic activity of surfactins" ppt
Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"
... patients.Introduction Chest radiographs (CXRs) are frequently obtained in intensive care units (ICUs) [1]. They can be obtained routinely, on a daily basis (so-called &apos ;daily routine CXRs'); such radiographs ... 7(page number not for citation purposes)Vol 10 No 1ResearchThe clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is lowMarleen E Graat1, ... chest radiographs (% of all daily routine chest radiographs) . bAbsolute number of patients (% of all patients with daily routine chest radiographs) . -, not scored for; ICU, intensive care unit. Table...
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Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf
... al. Maslinic acid targets on Plasmodium falciparumFEBS Journal 278 (2011) 29512961 ê 2011 The Authors Journal compilation ê 2011 FEBS 2961 Multi-targeted activity of maslinic acid as an antimalarial natural ... &Daniel H (2005) Maslinic acid, a natural compound from olives, induces apoptosis in HT-29 human coloncancer cell line. FASEB J 19, A996.8 Reyes FJ, Centelles JJ, Lupianez JA & Cascante ... process of the parasite infective cycle, favouring the appearance of resistant mutants which are easily spread in areas under chemotherapeutictreatments. Maslinic acid (MA) is a low toxic natural...
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Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt
... has GTPase activity FEBS Journal 277 (2010) 511525 ê 2009 The Authors Journal compilation ê 2009 FEBS 525 Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone ... that TorD has only a low level of this activity in vivo. Most GTPases bindvery stably to GTP and have a very low intrinsic level of GTPase activity, and also require the action of GTPase activating ... biological systems that utilise domain swapping to regulate activity. For example,glyoxylase I of Pseudumonas putida is a metastable domain- swapped dimer with two Zn2+cofactors thatalso exists as...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... in vivo footprinting as being protected in G0cells. The Cdc25C gene is not expressed in resting cellsor in cells in G1phase. Only in G2phase can strong transcription of the gene be detected. ... ARTICLE The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription Gerd A. Muăller and Kurt EngelandMolecular Oncology, Department of Obstetrics ... because inversion of the site in the humanCdc25C promoter resulted in a deregulation of cell cycle-dependent transcription. Deregulation is alsoobserved when the CDE alone is inverted [26].Interestingly,...
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc
... independentproteins and peptides leads to the disassembly of the spherical capsid inside the virion. Some of the foldeddomains of Gag are then able to reassemble as inde-pendent proteins. The matrix protein ... diverse CA–CA interactions and inter-faces involved either in the assembly of the immatureHIV-1 capsid, or in the reassembly of CA into amature capsid. The detailed description of the structureand ... substantial evidencefor the occurrence of different conformational rear-rangements of CA during the assembly of both the immature and the mature capsid of HIV-1 and otherretroviruses. Induced conformational...
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Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx
... Mapping of ATP and pNPP binding sites of the Na pump (Eur. J. Biochem. 271) 3927 The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site Rita ... IIand its position in the binding site was optimized.ResultsEffects of truncation of the cytoplasmic H4-H5 loop of the a subunit of Na+/K+ ATPase on TNP -ATP binding andp-nitrophenylphosphatase ... at the ATP and pNPP sites on the N-domain of the H4-H5 loop of Na+/K+ ATPase. The models u sed for (A–D ) are the same a sin Fig. 5. (A) and (C) This comparison of pNPP binding to the ATP...
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Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx
... The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments Youhei Yamagata1, Hiroshi ... near the C-terminal region on the opposite side of the N-terminal region on the molecular surface. In the wild-type enzyme, the side chain of Asp266 interacted with the amino group of the main ... conformational changeson the surface. On the other hand, anionic surfactants suchas SDS and LAS bind to the surface regions of protein, and the surface regions would be unfolded and removed from the core...
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Báo cáo khoa học: The hemoglobin genes of Drosophila ppt
... comprising of glob2 and glob3 is the earliest offshoot of the insect globins. Therefore, the separation of the glob2 ⁄ glob3 clade and otherinsect globins likely occurred early in the evolution of this ... globin genes, and almostcertainly reflect the ancient gene structure of the eukaryote globins [4]. Therefore, the loss and gain of introns occurred in the clade of glob1 and chironomidglobin genes ... reported the unprecedented occurrence of a hemoglobin gene(glob1) in the fruitfly Drosophila melanogaster. Here we investigate the structure and evolution of the glob1 gene in other Drosophila...
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Báo cáo khoa học: The specificity of alcohol dehydrogenase with cis-retinoids Activity with 11-cis-retinol and localization in retina docx
... consistent with the ADH4 activity previously found in this epithelium [25]. Thus, the presence in the RPE, the high activity with 11-cis-retinol, and the specificity for the oxidation direction of the ... ADH4 is detected in the retinal pigment epithelium (RPE) and itis extensively distributed in the retina. ADH4is found in the outer (ONL) and the inner(INL) nuclear layers, in the inner plexiformlayer ... the neural retina, together with the presence of receptors and otherproteins related to retinoic acid [21,60,61], indicate acomplex retinoid metabolism and signaling in retina, with the probable...
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Báo cáo khoa học: The transmembrane domain of subunitbof theEscherichia coli F1FOATP synthase is sufficient for H + -translocating activity together with subunitsaandc doc
... subunit bwhich are essential for the function of FOor the c ouplingto F1when reconstituted together w ith o ther FOsubunits.Whereas the soluble hydrophilic domain of subunit b hasalready ... the outer shell of the multilamellar proteoliposomeduring reconstitution [14,15], which is m ost likely due to the large h ydrophilic domain of the subunit b dimer. Thus, thiswould imply th ... obtained with a stoichiometric surplus of the latter. Recent studies dealing w ith the reconstitution of chloroform/methanol-extracted subunit c also revealed the necessity of an excess of the polypetide,...
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Báo cáo khoa học: The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity pot
... Sites for the design of inhibitors of PepX activity FEBS Journal 272 (2005) 20502059 ê 2005 FEBS 2051 The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design ... perform the automated molecular docking of the ligand valine-pyrroli-dide into DPP-IV and PepX active sites. The structure of DPP-IV complexed with valine-pyrrolidide [3] and the structure of PepX ... the specificity sites of DPP-IV and POP (Fig. 2B), the enzyme thatmost resembles DPP-IV (Fig. 1), the similarities appearcuriously lower than in the case of the superimposition of PepX and DPP-IV...
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Báo cáo khoa học: The antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes doc
... antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes Laure Be´ven1, Sabine Castano2, Jean Dufourcq2,A˚ke ... No activity at concentrations £ 100 lM.Ó FEBS 2003 Antibacterial activity of LK peptides (Eur. J. Biochem. 270) 2209 of action based upon the invasion of the outer membraneleaflet by the ... Hence, the anti-bacterial action of these peptides comprises four main steps:step 1, interfacial partitioning and exofacial accumulation of Fig. 5. Graphical illustration of the effects on antibacterial...
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Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot
... al. SRPK1 /1a inhibition by interaction with SAFB1 /2 FEBS Journal 27 6 (20 09) 5 21 2 522 7 ê 20 09 The Authors Journal compilation ê 20 09 FEBS 5 21 3 The enzymatic activity of SR protein kinases 1 and 1a ... GSTAnti-GSTAnti-FLAGAnti-GST 12 3 4 5 6 7 8 9 10 11 12 EluateFLAG–SRPK1FLAG–SRPK1aFLAG–SRPK1FLAG–SRPK1aFLAG–SRPK1FLAG–SRPK1aFLAG–SRPK1FLAG–SRPK1aBeadsFig. 5. Binding of the GST–SAFB1 /2 proteins on immobilized ... 4FLAGSRPK1aGSTNtLBRGSTSAFB2C (àg)GSTSAFB1CRE (àg) 12 34 5 6 12 3456 12 345 6 12 34 12 34 12 3 45666-45-35- 25 - 11 6-66-45-35- 25 - 12 2 Fig. 2. Effect of GST–SAFB1CDRE and GST–SAFB2C on FLAG–SRPK1a activity. ...
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Báo cáo khoa học: Structure and activity of the atypical serine kinase Rio1 doc
... 1. The structure and conservation of Rio1. (A) The structure of APO -Rio1 showing the important kinase domain features and the Rio1- specific loops (yellow). The P-loop, metal-binding loop and ... metal-binding, and flexible loops.(C) The alignment of the four molecules in the asymmetric unit of the crystals of Rio1- ATP-Mn.N. LaRonde-LeBlanc et al. Structure and activity of the Rio1 kinase FEBS ... with the uncomplexed protein. Com-parisons of the structure of Rio1 with the previously determined structure of the Rio2 kinase defined the minimal RIO domain and the distinct fea-tures of the...
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báo cáo khoa học: " The Puf family of RNA-binding proteins in plants: phylogeny, structural modeling, activity and subcellular localization" potx
... and involves the activity of an exten sive array of RNA-binding proteins. Throughout the lifetime of anmRNA, a d ynamic association exists between mRNAs and RNA-binding proteins. These interactions ... 10:44http://www.biomedcentral.com/1471-2229/10/44Page 9 of 19 RESEARC H ARTIC L E Open Access The Puf family of RNA-binding proteins in plants: phylogeny, structural modeling, activity and subcellular localizationPatrick ... analysis of the amino acids located in the amino-terminalextensions that lie outside of the PUM-HD in AtPum proteins. Acomparison of the percentage of amino acid identity and similarity for the amino...
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Từ khóa: tài liệu báo cáo khoa học bản chất của khủng hoảng kinh tế thế giới pdflam the nao de tom tat bao cáo khoa hocbáo cáo khoa họcbáo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnbáo cáo khoa học về cá trabáo cáo khoa học nghiên cứu chôm chômtrạng thái hiện sinh báo cáo khoa họcbiểu tượng văn học báo cáo khoa họctài liệu báo cáo khoa họccách trình bày báo cáo khoa họcNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam