Báo cáo khoa học: "Prevalence and Clinical Characterization of Gastric Helicobacter Species Infection of Dogs and Cats in Korea" pps

Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx

... be used in clinical immune ther-apy in order to induce immune responses in an anti-gen-speciﬁc manner in patients suffering from canceror viral infections [20].Cancer therapy is a principal ... theinsights gained by better understanding embryonichematopoiesis can meet clinical needs (in the ﬁelds of AIDS, immunotherapy, blood disorders and cancertreatment, for example) by helping ... importance of chemokine receptor 5 (CCR5) in HIV-1 infection; silencing of CCR5 in HSCs (by RNA interferencetechnology) yields HIV-1-resistant hematopoietic pro-genitors, potentially capable of restoring...

Báo cáo khoa học: Mycobacterium tuberculosis ClpC1 Characterization and role of the N-terminal domain in its function ppt

... shockproteins ClpP1, ClpC1, ClpX and ClpC2 have beenannotated. Bearing in mind the importance of the Clpfamily of proteins in survival and virulence, it is of interest to understand the mode of action ... N-domain, homologousto the N-domains of ClpA or ClpB, and a linkerdomain homologous to, but half the size of, thelinker domain of ClpB [19]. The N-terminal regioncontains two 32-amino acid ... triggered by a range of stress conditions, and is also induced in both the host and pathogenduring the process of infection [4].Heat shock protein, HSP100 or caseinolytic protein(Clp) is a highly...

Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf

... cobalamin at 0 min (thick solidline), 30 min (thin solid line), 60 min (thin long-dashed line),120 min (thin short-dashed line), 240 min (thin dotted line) and 360 min (thick dotted line) of incubation, ... model of damagedcofactors) for free adeninylpentylcobalamin (AdePeCbl)(an inactive coenzyme analog containing the adeninering in the upper axial ligand; a model of intact coen-zyme, AdoCbl) in ... min of incubation in the absence of ATP and Mg2+(thicksolid line) or without the reactivating factor in the presence of ATP and Mg2+(thick dotted line). (C) Time course of the reactivating...

Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

... obtained from injections of the metal into a solution of the protein. Typically an initial injection of 2 lL copperchelate solution was followed by a further 29 injections of 4 lL of Cu(II) into ... stage of tetramerization. Possibly, loss of copper binding could still allow domain swapping tooccur. It is of interest that a N-terminally truncated pri-on protein, lacking the copper binding ... Ratiokcal/mole of injectantkcal/mole of injectantkcal/mole of injectantkcal/mole of injectantkcal/mole of injectantkcal/mole of injectant-20-1-0.5 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0Stefin...

Tài liệu Báo cáo khoa học: Speciﬁc interaction between the classical swine fever virus NS5B protein and the viral genome pdf

... these minus-strand RNA fragments(Fig. 4 C). Therefore, t he 3¢ ÔCATATGCTCÕ sequence of 3¢ terminal of the minus-strand genome is essential tobinding of the CSFV NS5B protein. The minus-strand3¢ ... mechanism of initiation from the very 3 ¢ termina l of 3¢ UTR might be one of peculiarities of CSFV replicationbecause the sequence of the 3¢ terminal of 3¢ UTR isnecessary fo r binding of NS5B ... activity of the minus-strand3¢ UTR is stronger than the plus-strand 3¢ UTR in initiation of RNA synthesis. Indeed, it i s observed that agreater amount of plus-strand RNA than minus-strandRNA...

Tài liệu Báo cáo khoa học: "Extracting Comparative Sentences from Korean Text Documents Using Comparative Lexical Patterns and Machine Learning Techniques" doc

... comparative-sentence candidate, we use continuous words sequence within the radius of 3 (the window size of 7) of each keyword in the sentence; we expe-rimented with radius options of 2, 3, and 4 and we ... adverb and comparative, and RBS: adverb and superlative 153Our final goal is to find an effective method to extract S1 and S2, but single-keyword searching just outputs S1 and S3. In order ... of 88.54%, in our experiments using various web documents. 1 Introduction Comparing one entity with other entities is one of the most convincing ways of evaluation (Jin-dal and Liu, 2006)....

Tài liệu Báo cáo khoa học: "A Composite Kernel to Extract Relations between Entities with both Flat and Structured Features" ppt

... about 110 minutes and 30 minutes to do training on the ACE 2003 (~77k training in- stances) and 2004 (~33k training instances) data, respectively. (2) Further Improvement: One of the potential ... be handled by allowing grammar-driven partial rule matching and other approximate matching mechanisms in the parse tree kernel calculation. Finally, it is worth noting that by introducing ... the PT with the single in and out arcs of non-terminal nodes (except POS nodes) removed. (5) Flattened CPT (FCPT): the CPT with the single in and out arcs of non-terminal nodes (ex-cept...

Tài liệu Báo cáo khoa học: The tungsten-containing formate dehydrogenase from Methylobacterium extorquens AM1: Puriﬁcation and properties docx

... molybdopterin guanine dinucletoide cofactors of FdhH of E. coli (MGD801 and MGD802)thatwere found to be invariant among molybdopterin-containing FDH [34] are shown in red. Amino acids coordinating MGD801 ... molybdopterin binding family of FDHs. Fdh1A shares  40% of identical amino acidresidues with the catalytic a subunits of the two tungsten and selenocysteine-containing FDHs from Eubacteriumacidaminophilum ... position 140 of FDHH of E. coli. The alignment shown in Fig. 2 indicates that the sequence of FDH1 fromM. extorquens AM1 ﬁts well in the family of molybdopterin-containing FDH. All of the amino acid...

Tài liệu Báo cáo khoa học: A synthetic weak neurotoxin binds with low afﬁnity to Torpedo and chicken a7 nicotinic acetylcholine receptors docx

... 62–68 amino acids and belong to thestructural family of Ôthree-ﬁngeredÕ folded toxins, whichincludes the cardiotoxins, muscarinic toxins, acetylcholin-esterase inhibitors and the a-neurotoxins ... at equilibrium, the effect of toxins on the125I-labelled a-Bgtx binding. Varying amounts of toxinswere incubated with 3 nM of active sites of receptors and 5 nM of 125I-labelled a-Bgtx for ... 3¢ ends of primers used in RT-PCR are in bold and underlined. The regions coding for the putative signal peptides (CDS) and neurotoxins are shown. The encoded amino acids are indicated in capitalletters...

Báo cáo khoa học: Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states docx

... probes and optical spectroscopy are nowentering a phase enabling the in vivo interrogation of the role of oligomers in amyloidosis. Such techniques used in parallel with in vitro experiments, of increasing ... composed of theSH3 domain of PI3 kinase [42,43]. By mixing theselabelled proteins in a 50 : 50 ratio and following theaggregation process, their data revealed that the for-mation of oligomeric species ... a-synuclein,apolipoprotein C-II and insulin. To obtain information on the progression of the intermediate states, these were monitored in terms of ﬂuorescenceparameters, such as anisotropy, and quantum...

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