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Báo cáo sinh học: "SnoPatrol: how many snoRNA genes are there" pdf

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Báo cáo sinh học: " Determination of suitable housekeeping genes for normalisation of quantitative real time PCR analysis of cells infected with human immunodeficiency virus and herpes viruses" pdf

... AccessMethodology Determination of suitable housekeeping genes for normalisation of quantitative real time PCR analysis of cells infected with human immunodeficiency virus and herpes virusesSarah Watson1, ... Ref-erence gene selection for quantitative real- time PCR analy-sis in virus infected cells: SARS corona virus, Yellow fever virus, Human Herpesvirus-6, Camelpox virus and Cytomeg-alovirus infections. ... researchers of these viruses with a shortlist of potential housekeeping genes to use as normalisers for QPCR experiments.Background Quantitative real- time PCR (QPCR) is an invaluable tool for the...
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Báo cáo sinh học: "The Sturm-Liouville BVP in Banach space" pdf

... below).For information about publishing your research in Advances in Difference Equations go tohttp://www.advancesindifferenceequations.com/authors/instructions/For information about other SpringerOpen ... we approximate the singular fourth-order BVP to singularsecond-order BVP by constructing an integral operator. In Section 3, the sufficient condition for the existenceof single and multiple positive ... Sturm–Liouville BVP in Banach spaceHua Su∗ 1, Lishan Liu2and Xinjun Wang31School of Mathematic and Quantitative Economics, Shandong University of Finance and Economics, Jinan Shandong 250014,China2School...
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Báo cáo sinh học: "Controlling how many cells make a fly" ppt

... as starvation, decreasesignaling activity within the pathway,which in turn drives the worms intothe developmentally arrested ‘dauerstage’ (DAF denotes ‘dauer forma-tion’). Dauer larvae alter ... DAF-16 isalso disabled, the worms develop asnormal. The clear implication is that innormal animals the insulin pathwayhas its effects on dauer formation vianegative regulation of DAF-16. “But ... In many waysthis is similar to the situation inmammals, where mutations in theinsulin/IGF pathway affect growth andbody size. The flies have fewer cells, and the cells they do have are smallerin...
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Báo cáo sinh học: "The functional landscape of mouse gene expression" pdf

... currentabsence of knowledge of the physiological functions of atleast half of all mammalian genes. Given that distinct andcoordinate expression of a group of functionally relatedgenes implies ... Number of genes definedas expressed in each of the 55 tissues, using criteria in (a).Number of expressing tissuesNumber of genesarcsinh (normalized intensity)Proportion of values (%)Number of ... a blind test, the known genes in many functional categories can be distinguished on the basis of the expres-sion profiles of other genes that are members of the same functional category. This...
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Báo cáo sinh học: "Co-regulation of mouse genes predicts function" pps

... mountain of microarraydataHughes’ first concern was which genes to spot onto his microarray slides (seethe ‘Background’ box). Researchers areResearch newsCo-regulation of mouse genes predicts ... preliminaryfunctional annotation for thousands of genes of unknown function is a majoradvance.” The Hogenesch group is alsocreating an atlas of mammalian genes [5]. “This approach had been used inyeast ... hypotheses for the roles of thousands of genes in the genome.”An open resource at the click of a mouse Hughes’ analysis revealed that theresults from the extensive mouse tissue-specific dataset...
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Báo cáo sinh học: " CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo" pdf

... providerapid in vitro screens for analyzing new therapies and discovering means of achieving selective protection ortargeted killing. In light of the ease of use of these in vitro and in vivo assays, ... Research article CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivoJoerg Dietrich*, Ruolan Han*, Yin Yang, Margot Mayer-Pröschel and Mark NobleAddress: ... solution).Immunofluorescence and TUNEL staining in vivoFree-floating sections (40 àm) were used for all in vivoexperiments for TUNEL staining and combined immuno-fluorescence staining. Detection of nuclear...
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Báo cáo sinh học: " The eleven-year switch of peptide aptamers" pdf

... some of the aptamers tested have been shown to inhibit the function of their cognate targets and to cause phenotypesin the experimental models in which they were expressed. The use of peptide ... orders of magnitude.This work opens the way to an important extension of the therapeutic research applications of peptide aptamers,which are already used throughout the multi-step process of drug ... shapesrepresent the cognate target proteins of the aptamers with matching colors. Protein detection is illustrated only for the first row of peptide aptamers. The binding of a protein to its cognate peptide...
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Báo cáo sinh học: " NFIX - one gene, two knockouts, multiple effects" pdf

... acceptor1a/1b35′ splice acceptor1a/1b 3loxPX-NYX-FreiburgNFIANFIB-NYNFICNFI wild-type allele1a/1bPGK-neo3LacZ1a/1b3NFIB-FreiburgLacZ-neo1a/1b31a/1bPGK-neo 3Transcript1 231 213+1 ... 77::29 (P) 2 1-2 8. The X-NY strain, on the other hand, did notsuffer from such severe impairments. Callosal agenesis asseen in the X-Freiburg strain was not noted in X-NY NFIX -/ - animals. The ... along the dorsal-ventral axis, hippocampus forma-tion is aberrant, and overabundant Pax 6- and doublecortin-positive cells are found in the lateral ventricles of X-NY mice.When the X-NY mice were...
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Báo cáo sinh học: " Lateral inhibition and concentration-invariant odor perception" pdf

... ORNsactivated by an odor increases with odor concentration -thus creating a shifting odor representation in the antennallobe. Despite this, Drosophila larvae can navigate towards anattractive odor source ... in Journal of Biologysuggests that lateral inhibition in the Drosophilaantennal lobe is similarly required for concentration-invariant perception of odors.Journal of Biology 2009, 88::4Published: ... - that a given odorant excites multiple ORNs and a givenORN responds to multiple odorants [1,9]. In principle, acombinatorial code using the glomerular pattern can encodemore odors than the...
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Báo cáo sinh học: "Representations of odor plume flux are accentuated deep within the moth brain" ppsx

... pheromoneand other odorant signal processing and odor- quality discrimination. The anterior face of the moth is looking up toward the top of the figure. Sexpheromone information comes into the antennal ... odor- flux peaks of the plume s pheromone strands and the troughs of the clean air pockets are sharpened by the antennal lobe’sinhibitory circuitry, and their temporal integrity is keptintact deep ... Axons from each of these classes of pheromone-component-tuned ORNs travel to the antennallobe of the brain at the base of the antenna and arborize intheir own class-specific knot of neuropil called...
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Báo cáo sinh học : "Q&A: Genetic analysis of quantitative traits" pdf

... to Quantitative Genetics, 4thedition.Harlow, Essex: Longman; 1996.Lynch M, Walsh B: Genetics and Analysis of Quantitative Traits. Sunderland, MA:Sinauer; 1998.Published: 17 April 2009Journal of ... environments. Theseresources offer the prospect of elucidating the genetics of theinterdependence of multiplephenotypes, and addressing thelongstanding question of the genetic basis of genotype-environmentinteraction.WWhheerree ... have23.4Journal of Biology2009, Volume 8, Article 23 Mackay http://jbiol.com/content/8/3/23Journal of Biology 2009, 8 8:: 23 Question & AnswerQQ&&AA :: GGeenneettiicc aannaallyyssiiss ooff...
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Báo cáo sinh học : "The genetics of gender and life span" pdf

... ooffffssFinding mechanisms that explain the difference in life spanbetween males and females is hindered by our lack of understanding of the basic mechanisms of aging and underlying causes of ... 8 8:: 38Published: 29 April 2009Journal of Biology2009, 8 8:: 38 (doi:10.1186/jbiol141)The electronic version of this article is the complete one and can befound online at http://jbiol.com/content/8/4/38â ... of inbreeding provide additional insight into the geneticarchitecture underlying life span differences between genders in two different insects.Journal of Biology 2009, 8 8:: 38Published:...
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Báo cáo sinh học: "The effects of lipids on channel function" pdf

... compositions of the cells expressing connexin26 and connexion32 are slightly different.Collective physical propertiesBecause high concentrations of anionic lipid are needed to affect channel ... interface, and similar charge interactions are likely to be important for other channels. It is also likely that the effects of anionic lipids on channel function follow directly from binding to ... 7:52.2. Marius P, Zagnoni M, Sandison ME, East JM, Morgan H, Lee AG: Binding of anionic lipids to at least three nonannular sites on the potassium channel KcsA is required for channel opening....
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Báo cáo sinh học: "SnoPatrol: how many snoRNA genes are there" pdf

... SnoPatrol: how many snoRNA genes are there? Journal of Biology 2010, 9:4.Page 4 of 4 that for many major taxonomic clades there are few or no known snoRNAs annotated.In the Archaea, annotated snoRNAs ... 1. snoRNA structure. The structure of a H/ACA snoRNA (left) and a C/D box snoRNA (right). The targets for RNA modification are shown in blue. The most important snoRNA- associated proteins are ... further projects are in progress, yet despite this apparent wealth of information no snoRNAs have been identified. But like diplomonads, micro sporidia clearly have components of the snoRNA machinery...
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Báo cáo sinh học: "Support for single major genes influencing fat androstenone level and development of bulbo-urethral glands in young boars MN Fouilloux" potx

... finding of a major gene affecting fat androstenone level gives rise to newprospects for reducing incidence of boar taint by means of breeding. The average level of individuals ... results of a selection experimentbased on an index associating fat androstenone level and bulbo-urethral gland size. In: Measurement and Prevention of Boar Taint in Entire ... standard deviation units of thetrait for the ’Box-Cox transformed’ data. Corresponding genotype means on the Original articleSupport for single major genes influencing fat...
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