... with other metabolic dis eases like
hypercholesterolaemia and diabetes; each of them is
further and effectively treated with the association of
different compounds [9,10].
Even autoimmune dise ... in the last decade, the approaches
to cancer therapy have change d. In 1998, the approval of
trastuzumab for the treatment of breast cancer was a mile-
stone which establishe...
... bad they want to
get out of t here and if their country is forcing them to
stay - that’s not good for the individual.” The literature
also suggests that the migration of health professionals
is ... lessen the
migratory flows without addressing the ‘push’ or the
non-medical sources of high disease burdens in poorer
countries) is wrong-headed by attacking the sympt...
... attempt to better understand
the mechanism of action of HRSV neutralizing antibodies
and the impact of resistance to these antibodies upon the
fusion activity of the F protein. A summary of these ... of con-
servation, it was somewhat surprising that the functional
analysis of the fusion activity of the panel of mutations
described here revealed that the...
... CyP's capacity to impair innate resistance to
HSV-1 [56,57]. Further study is needed to test this
hypothesis.
Role of Stat 1 in innate resistance to HSV-1
The biological functions of IFN-α/β and ... [1-3]. This observa-
tion has fostered the belief that NK cells play a central role
in innate resistance to HSV-1 infection. This hypothesis is
further supported by the...
... viral isolates 3H was caused by the value of 0 of d
S
at the
denominator. The positive selection on the domain III is
not surprising since domain III contains the receptor-
binding domain and major ... from
0.22–0.39% of mean p-distances in this study. These val-
ues are within the range calculated by other studies (0.12
to 0.84%) for different portions of the E pro...
... require new ways of thinking
and the help of mathematicians and
physicists. These approaches are being
incorporated into the broad field of
‘systems biology .
To help the application of this tech-
nology ... Obviously
these phenotypes overlap in many
cases, so that the effects of each RNAi
can be defined in terms of its pheno-
typic profile. Christophe Antoniewski,...
... contribute to the effects of chemo-
therapy on cognition. The ability of irradiation to the CNS
to suppress the generation of new neurons in the hippo-
campus has been suggested to be relevant to the
understanding ... analysis also provided the first demonstration of
delayed effects of chemotherapy on the latency of impulse conduction in the auditory sy...
... after
glacial cycles.
Journal of Biology
2008,
77::
32
Published: 3 November 2008
Journal of Biology
2008,
77::
32 (doi:10.1186/jbiol90)
The electronic version of this article is the complete one ... Department of Ecology and
Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada M5S 3B2. Email: allanb@rom.on.ca
The general cooling of the wor...
... ‘cause’ of CL/P. Importantly, none of the variants
identified resides within the MH1N or homeodomain
regions harboring the tooth-agenesis mutations; rather, they
locate to other regions of the protein, ... only limited insights into the pathogenicity of heterozygous
missense substitutions in human genes.
Journal of Biology
2009,
88::
26
Published: 24 March 2009
Jo...