... modules of the tandem construct thanin the free modules, with increases apparent at the interfaces A–B (E300), D–E (Y325) and C–D (Y3 81) ,near the F–G turns of CCP2 (T 411 , C 412 , I 417 and W 418 ) and ... GJ (2009) Identification of the C1q-bindingSites of Human C1r and C1s: a refined three-dimen-sional model of the C1 complex of complement. J BiolChem 284, 19 340 19 348. 13 Kardos J, Ga´l P, ... ± 12 .3 ms), (C) { 1 H}- 15 N NOE (0.608 ± 0 .16 3) and (D) R2⁄ R 1 of CCP1CCP2 at pH7.0, 315 K (filled circle) and of CCPsingleat pH7.0, 300 K (hollow triangle). The positions of the b-strands...