... withadvanced cancer and pain. J Pain Symptom Manage 2002,23:526-532.83. Khojainova N, Santiago-Palma J, Kornick C, Breitbart W, GonzalesGR: Olanzapine in the management of cancer pain. J PainSymptom ... Carbamazepine acts as aninducer of cytochrome 3A4 , which may increase the metabolism of some anticoagulant and cardiovascularmedications. Olanzapine may induce or worsen cardiacrisk factors such as obesity, ... http://www.general-hospital-psychiatry.com/content/3/1/7Page 6 of 10(page number not for citation purposes) of portacaval shunting, thereby decreasing first passmetabolism; decrease in quantities and affinity of plasmaproteins, thereby increasing...