... Chapter 105. Malignancies of Lymphoid Cells (Part 9) Two other features may be used to assess prognosis in B cell CLL, but neither has yet been incorporated into a staging ... g/dL)] and number of extranodal sites with number of nodal sites (more than four). Low risk (zero or one factor) was assigned to 36% of patients, intermediate risk (two factors) to 37%, and poor ... classification. At least two subsets of CLL have been identified based on the cytoplasmic expression of ZAP-70; expression of this protein, which is usually expressed in T cells, identifies a subgroup...