... renal disease: Clearance, urinalysis and renal biopsy, in Brenner & Rector's The Kidney, 7th ed, Chapter 045. Azotemia and Urinary Abnormalities (Part 8) Approach to the patient ... reabsorption and indirectly reduces the responsiveness of the tubule to aldosterone. Usually, the Na losses are mild, and the obligatory urine output is <2 L/d (resolving ATN and postobstructive ... diabetes insipidus. For a detailed discussion, see Chap. 334. Further Readings Anderson S et al: Renal and systemic manifestations of glomerular disease, in Brenner & Rector's The...