... headachea Rheumatoid arthritisa,b Chronic low back painb Cancer Chapter 012. Pain: Pathophysiology and Management (Part 8) Antidepressant Medications The tricyclic antidepressants ... as orthostatic hypotension, drowsiness, cardiac conduction delay, memory impairment, constipation, and urinary retention, are particularly problematic in elderly patients, and several are additive ... patients opioid analgesics are the best available option. This is understandable since opioids are the most potent and have the broadest range of efficacy of any analgesic medications. Although...