... Revised 31 July 2008; Accepted 31 July 2008 Extractive electrospray ionization mass spectrometry (EESI-MS) for real-time monitoring of organic chemical reactions was demonstrated for a well-established ... etc.),16showing its potential for on-line, real-time monitoring of trace amounts of chemicals.We have extended the application of EESI to instantlyfollow organic chemical reactions in a straightforwardmanner, ... L. Zhu et al. Real-time, on-line monitoring of organic chemical reactions using extractive electrospray ionization tandem mass spectrometry Liang Zhu1, Gerardo Gamez1, Huan Wen Chen2**,...