... Unit, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland, 3Division of Hematology and Transplant, Department of Clinical Medicine and Immunological Sciences, University of Siena, ... chromosome 13q14.3deletion, occurring in half of the cases [4]. The deletion isoften interstitial and can be homozygous in up to 15% of the cases [4]. When it represents the only lesion it is asso-ciated ... [119], and canplay an indirect role in BCR signal transduction, mainlymodulating events at the end of the signaling response[120]. Expression of ZAP-70, which can enhance and pro-long on syk and...