... emerged from Finland, suggestingthat the lack of CCR5 does not protect from MS, but ratherit may predispose to the chronic course of the disease [69].This would further imply that in view of the ... purposes)macrophages and resident microglia to sites of CNS inflammation. Detailed knowledge of expression patterns is crucialfor the understanding of therapeutic modulation and the validation of CCR1, CCR2 and ... immu-noneutralization of CCL3 [44], DNA vaccination [45], orgenomic deletion of the CCR1 gene [22], reduces clinicaldisease. Taken together, the results of the present study and from previous ones on the role of...