... purposes)Journal of Translational MedicineOpen AccessResearchInterdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cellsKeith M Skubitz*1 and Amy PN Skubitz2Address: ... on neutrophil adhesion to endothelial cellsBecause CEACAM-1, -3, -6, and -8 are highly homologousstructurally, and can undergo a number of differenthomotypic and heterotypic adhesion reactions ... ligation of CEACAM-1, -8, -6, and -3 byCD66a, CD66b, CD66c, and CD66d mAbs, respectively,transduce signals in neutrophils resulting in activation of CD11/CD18, and an increase in neutrophil adhesion...