... intense). Positive ratescore of cancer cells was: 0-10% was recorded as 0; 10-30% was recorded as 1; 30-50% was recorded as 2; 50-75%was recorded as 3; > 75% were recorded as 4. The expres-sion ... model.Journal of Cell Biology 2010, 188:11-19.12. Deisboeck TS, Couzin ID: Collective behavior in cancer cell populations.Bioessays 2009, 31:190-197.13. Polyak K, Haviv I, Campbell IG: Co- evolution ... hasbeen recognized that inva sion is regulated not only by* Correspondence: liyansd2@163.comDepartment of Oncology, Zhongnan Hospital of Wuhan University, HubeiKey Laboratory of Tumor Biological...