... A minor, splicing-independent pathway invol-ving endonucleolytic cleavage within the intron hasalso been identified in yeast and rat [33,45–48]. In addition, in plants and certain yeasts, snoRNAs ... a single gene can host several snoRNAs in various introns, but a gene contains in general onlyone intronic miRNA, or one cluster of miRNAs in asingle intron. The single known exception for ... (follistatin-like) gene, and for hsa-mir-133a-2, located in the C20orf166 gene thatencodes a potential 117 amino acid protein. In addi-tion, hsa-mir-21 probably resides in the sense orienta-tion in...