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báo cáo hóa học:" Response shift, recall bias and their effect on measuring change in health-related quality of life amongst older hospital patients" pdf

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báo cáo hóa học: " Dental pain, oral impacts and perceived need for dental treatment in Tanzanian school students: a cross-sectional study" docx

... "available and in workingcondition" or (0) "not available and/ or not in workingcondition." These assets were analyzed using principalHealth and Quality of Life Outcomes 2009, ... Locker D: Concepts of oral health, disease and the quality of life In: Slade G, ed. Measuring oral health and quality of life. In Dental Ecology Chapell Hill: University of North Carolina;1997:11-23. ... 2). Oncethe main effects were established, all pairwise interactioneffects were examined. Two-way interactions occurredbetween problems sleeping and problems eating on theone hand side and...
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báo cáo hóa học: " Comparing the SF-12 and SF-36 health status questionnaires in patients with and without obesity" pot

... Edelman D:Relationship between obesity and health-related quality of life in men. Obes Res 2002, 10(10):1057-64.20. Finkelstein MM: Body mass index and quality of life in a survey of primary care ... improvement in co-morbidconditions, change in quality of life and patient satisfaction.Obes Surg 2003, 13(6):954-64.3. Horchner R, Tuinebreijer MW, Kelder PH: Quality- of- life assess-ment of morbidly ... ourfindings longitudinally and in more diverse populations.Competing interestsThe author(s) declare that they have no competing inter-ests.Authors' contributionsCW conceived of the...
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báo cáo hóa học:" Cancer stem cell subsets and their relationships" pot

... invasion in matrigel, accompanied with increased expression of E-cadherin and reduced expression of vimentin and b-catenin. Furthermore, they transplanted SUM149 cellsinto athymic nude mice and ... demonstrated that erlotinibinhibited the growth of tumor and lung metastasis byregulating the expression of E-cadherin and vimentin.This study suggests that erlotinib reversed EMT of IBCto inhibit ... can-cer. They demonstrated that Lgr5 positive or prominin1positive subpopulations were intesti nal stem cells. Dele-tion of Apc or activation of endogenous Wnt signaling in such intestinal stem cells...
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báo cáo hóa học: " Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice" doc

... occurs in later stages of brain injury. The significant findings of increased T cell i nfiltrate into the injury site, increasedlevels of IL-2, prolonged neuronal death surroundingthe injury ... MT-I/II-/-mice.ConclusionsMT-I/II expression is increased in the brain after braininjury which su ggests that some of the protective effects of MT-I/II after brain injury are acting directly on theinjured brain. ... implication of these findings is that MT-I/IImay be having effects on the immune system systemi-cally hence MT-I/II may be affecting the progression of brain injury indirectly via modulatio n of inflammatoryresponses.A...
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báo cáo hóa học:" Genetic Barriers to Resistance and Impact on Clinical Response" pptx

... combination of mutations, might have agreater effect than others. Thus, defining the genetic bar-rier entails more than simply counting mutations; it alsoinvolves determining the effect of single ... EFVThe combination of TDF + ddI + EFV represents a potent and convenient once-daily combination. Clinical datahave shown this regimen to maintain viral suppressionupon treatment switches among patients ... Program and abstracts of the 5th International Congress on DrugTherapy in HIV Infection; Glasgow United Kingdom 2001. Abstract 26917. Gallant JE, Rodriguez AE, Weinberg W, et al.: Early non -response to...
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báo cáo hóa học:" Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells" pdf

... immunotherapeutic inter-ventions are promising, current treatments to induce strongimmune responses against HCMV are still inadequate. In order to develop a new method to induce strong immuneresponses against ... higherlevels of CD80, CD83, CD86, and CD1a over controls. In fact, the DC-loading technique was found to be highlyeffective in generating significant CTLs with only one DC-T-cell co-incubation and in ... responses against HCMV, includingthe major immediate-early protein (IE) [18], glycoprotein B(gB) [18], and non-envelope structural virion proteins, suchas the matrix protein pp65 [19]. Among...
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báo cáo hóa học:" Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer" doc

... the CHK1 inhibitors (A) SB 218078 or (B) PD 407824 in combination with vary-ing concentrations of gemcitabine resulted in a shift of the dose response curves suggesting potentiation of the gemcit-abine ... potentiation of gemcitabine response in (A) MIA PaCa-2 and (C) BxPC3 cells as seen by the shift in the dose response curves. Silencing of CHK2 did not affect the response to gemcitabine in either ... pancreaticKinetic analysis of CHK1 siRNA induced sensitization of gemcitabine responseFigure 4Kinetic analysis of CHK1 siRNA induced sensitization of gemcitabine response. MIA PaCa-2 cells were...
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báo cáo hóa học:" Announcing the Tumor Immunology and Biological Cancer Therapy section (edited by iSBTc) of the Journal of Translational Medicine" ppt

... Executive Office, Chloé Surinak monitors and supports the subsection interactions with the iSBTc leadership, its membership and BioMed Central; Tara Withington as Executive Director of the iSBTc ... here:http://www.biomedcentral.com/info/publishing_adv.aspBioMedcentralJournal of Translational Medicine 2009, 7:80 http://www.translational-medicine.com/content/7/1/80Page 2 of 2(page number not for citation purposes)Pedro ... Central and every scientist can read your work free of charge"BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime."Sir...
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Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx

... compari-son of pre- and post-vaccination responses to ind ividualpeptides showed that both boosting and reduction of pre-existing responses occurred and also that newT-cell specificities could be induced ... report on administration of aHer2-pDNA vaccine in humans. We demonstrate thatinjection of the pDNA vaccine and cytokines duringconcurrent trastuzumab treatment was safe, well toler-ated and induced ... subgroup of patients.Conclusion: This pilot clinical trial demonstrates that Her2-pDNA vaccina tion in conjunction with GM-CSF and IL-2administration is safe, well tolerated and can induce long-lasting...
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Báo cáo hóa học: "Immuno-Oncology Biomarkers 2010 and Beyond: Perspectives from the iSBTc/SITC Biomarker Task Force" pot

... the inherent variability of patients, variability of col-lection and processing of their blood and tissues, of selec-tion and conduct of assays, and of the informationreported on samples and ... useful information on early and late cellular immune responses and may have clini-cal utility in the assessment of cellular changes in response to various disease and treatment. Simplification and ... processing and banking; standardized functionalassays, thorough reporting of details and controls in pub-lications, and banking of not only blood and serum butalso patient DNA, tumor cells and...
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