... ascites. Ovariancancer a scites OVC432 had little anti-apoptotic activityagainst cisplatin, paclitaxel and TRAIL. These datademonstrate that the inhibitory effect of ascites againstdrug cytotoxicity ... were available for a ll patients and diseases were classified as benign or malignantaccording to the histology. To characterize the prosurvi-val activity of the peritoneal fluids against TRAIL, ... hadinitial similar tumor burden. Our data raise also the possibility that EOC cells survive in the peritoneal cavitydespite active therapy, at least in part, due to the actionof anti-apoptotic factors...