... et al.: Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments. Annals of Intensive Care 2011 ... 1:32http://www.annalsofintensivecare.com/content/1/1/32Page 9 of 9REVIE W Open Access Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developmentsPatrick ... disturbances [80].New perspectives for medical treatment of septic AKI With septic AKI seen as an apopt otic-inflammatory AKI, the administration of caspase inhibitors (CI) gains increas-ing interest....