... study.
A limitation of this assay is that an increase in the mean
percentage of PBMCs displaying p-STAT-3 was not
detected in all cases of malignant gliomas; however, an
elevation in this value during ... may lead to continued growth and
increased malignancy. In many malignancies, the signal
transducer and activator of transcription 3 (STAT-3) plays
an integral role in...
... Y
i
is and is the ML estimate of the
covariance of Y
i
. The ML estimates assume the missing
data mechanism is ignorable and are calculated on the
available data. It follows that is the J
{p} ... 1324) – evaluating the clinical- and cost-
effectiveness of symptomatic versus intensive biphospho-
nate therapy for the management of Paget's disease. QoL
was asses...
... categories are evaluated. Cover-
age was examined by calculating the number of activities
and participation component domains included in each
instrument and the percentage of questions containing
ICF ... domains. In
the PARTS/M, for each of the 20 aspects of participation
included there is a question which asks if either 'pain'
(b280 Sensation of pain) or &a...
... awareness of a patient's
subjective perception of the disease and the daily limita-
tions they face [6]. There are various possible ways of
assessing HRQoL. The importance of using disease-spe-
cific ... impacts of a disease on daily life,
they allow investigations in large populations.
Considering the advances in CF therapy and with regard
to the recent incre...
... provided inputs on design and revised
the manuscript during the writing. All authors read and approved the final
manuscript.
Competing interests
The authors declare that they have no competing interests.
Received: ... [18].
The questionnaire was mailed to a sample of members
of the Norwegian Diabet es Association. A large
proportion of the individuals with type 1 dia...
... participated in the design of the study and performed the statistical
analysis and interpretation of data, and drafted the manuscript; ML
participated in the design of the study and the statistical analysis ... analysis.
Pharmacoeconomics 2008, 26:769-779.
10. Amjadi SS, Maranian PM, Paulus HE, Kaplan RM, Ranganath VK, Furst DE,
Khanna PP, Khanna D: Validating and Asse...
... through a visual analog scale (a 0–1 00 scale that
elicits a numerical representation of self-perceived overall
health). The visual analog scale in particular allows for an
encapsulation of all affected ... various domains of health, ranging from
things like vision and dexterity to social functioning and
vitality. These domains are intended to capture the range
of aspects...
... Sari Andajani-Sutjahjo and Ms Catherine Bai-
ley for their assistance with the data management, and Professor Alan Ten-
nant for assistance with the statistical analyses. We also acknowledge the ... a standard-
ized, validated generic instrument and is available in Thai,
Malay, Bahasa Indonesia, and Chinese [28], and was
included in the study not only to provide a health statu...
... successful treatment for PE.
In addition to inquiring about the general impact of PE,
the in- depth interviews included administration of the
male and female partner versions of the single item PE
measures ... like there's a large part of you that is miss-
ing or failed." In addition to inadequacy, many of the men
reported feeling anxious, frustrated, an...
... alkaloid which is produced in tobacco
plants as a result of the leaves' being damaged [1,2]. The
roots of the damaged plants synthesize nicotine as a reac-
tion to hormones released by the ... Bioengineering, Fulton School of Engineering ASU,
Tempe AZ, USA
Full list of author information is available at the end of the article
Akkurt et al. Journal of NeuroE...