báo cáo hóa học:" Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other "virus receptor" diseases" doc
... Journal
Open Access
Hypothesis
Replicative homeostasis II: Influence of polymerase fidelity on RNA
virus quasispecies biology: Implications for immune recognition,
viral autoimmunity and other ... diversity and immune recognition under influence of Replicative homeostasisFigure 7
Conceptual progression of intracellular viral replication ev...
... Central
Page 1 of 20
(page number not for citation purposes)
Virology Journal
Open Access
Hypothesis
Replicative homeostasis II: Influence of polymerase fidelity on RNA
virus quasispecies biology: Implications ... variable RNA
pol
fidelity and processivity, restriction of antigenic diversity and immune recognition under influence of Replicative...
... number not for citation purposes)
a. Constraints on viral mutationFigure 3
a. Constraints on viral mutation. Inadequate polymerase fidelity will cause loss of sequence information and quasispcies ... accumulation of variant viral
proteins causes progressive, direct, inhibition of RNA
pol
and also block Env
Wt
:RNA
pol
interactions that increase
replication and...
... clear
correlation between results of immune monitoring and
clinical benefit in terms of tumor responses. This lack of
correlation of immune parameters and response may
relate to the likely low sensitivity of ... rol
(objective responses by RECIST plus SD beyond 8
weeks)rateof20%,anullresponserateof5%,atype
one error of 0. 10, and a type two error of 0.10. As such,
cont...
... degrees of flexion) and open reduction and
internal fixation of displaced type III, IV and V. Some
authors regret not fixing type I and II fractures, with
subsequent loss of reduction and unsatisfactory ... months post-operative radiographs.
Journal of Orthopaedic Surgery and Research 2009, 4:23 http://www.josr-online.com/content/4/1/23
Page 2 of 5
(page number n ot for...
... attention in 2 of the 4 sessions with this simu-
lation and fatigue in 3 of the 4 sessions. S2 demonstrated
decreased attention during three of his 4 sessions and
fatigue during 4 of his sessions ... simulation with no attention lapses, no
demonstrations of fatigue and unanimous agreement that
the simulation was fun and an option for future sessions.
The other simulation...
... examination of affected joint and
other selected jo ints consisted of range of mot ion tests
and resisted motion maneuvers (table 1). Range of motion
data were recorded as described by Rompe and Erlenkäm-
per ... adduction of the fingers (with resistance)
Extension and adduction of the thumb (with resistance)
Cervical Spine
Rotation in normal position (neutral)
Rotation...
... cost of ART is based on a unit cost of P3599 in
2010 and P4135 in 2015 for first-line antiretrovirals
(ARVs) with an additional $133 for second-line ARVs
[18].
In addition, we assume continuation ... reduce the number of new HIV
infections in men, the number of new HIV infections in
Number of male circumcisions performed by scenarioFigure 1
Number of male circumcisions per...
... C. Li, “The existence of infinitely many solutions of a class of nonlinear elliptic equations with
Neumann boundary condition for both resonance and oscillation problems,” Nonlinear Analysis:
Theory, ... Article
Multiple Solutions of p-Laplacian with
Neumann and Robin Boundary Conditions for
Both Resonance and Oscillation Problem
Jing Zhang and Xiaoping Xue
Department of...
... solution of the aperture problem, a hysteresis effect
in the temporal update of the motion representation given
contradicting evidence for motion direction, and the motion
interpretation for configurations ... feedback
connections, the RF field size ratio between V1 and MT,
and, as a prediction of our model, the spatial extension of
the region of ambiguous motion. The time cou...