... to induction of inflammatory signal transducing factors including cyto-kines, chemokines, complement, and stress response pro-teins which we and others have previously described in studies of ... normal brain aging, but characterization of hippocampal cellular and molecularmediators of immune/inflammatory signaling in cogni-tively stratified subjects remains incomplete. Studies of severe ... cognitively intact and aged cognitivelyimpaired rats compared to adults. (B) Iba1, a microglia-specificcalcium binding and actin-bundling protein, is significantly induced in CA1 and CA3, but not DG of...