... In anotherreport, depletion of Lin-9, Lin-37, Lin-52 or Lin-54 byRNAi also led to a repression of genes, such as cyclinA and cyclin B1, in dividing cells [92]. Furthermore,depletion of Lin-9 ... upregulation would indicate a function of Lin-9 in repression. This indicates that Lin-9 is involved in the activation of these genes in cycling cells. In summary, it has been shown that the DREAMcomplex ... However, as in most other CDE ⁄ CHRpromoters, mutation of the CHR results in a smallerremaining cell cycle- regulation than alteration of the CDE [37]. Interestingly, the core of the human Tome-1promoter...