... ICT, and by the condition (thalassemia, SCD, MDS).Figure 1 provides an overview of the hypotheses for the impact of infusion ICT on the QoL of patients with ironoverload. In thalassemia, the impact ... that the impact of such therapy includedpain at the injection site (3/9 [33%]), although onepatient reported that the problem was not the pain from the injection site but rather awareness of the ... ascertain the direct impact. Nevertheless, even with the aforementioned caveats, ourresults indicated that the impact of infusion ICT on QoLis high. There is a need for easier oral iron chelation ther-apy...