báo cáo hóa học: " Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord" potx
báo cáo hóa học: " Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord" potx
... important in under-standing changes in demyelination and remyelination in the NG2 null mouse. Although it remains to bedetermined whether changes in cytokine expression in the NG2 null mouse are ... in wild type mice, with both myelin damage and repair being reduced in the NG2 null mouse. These studies identify NG2 as an important factor in regulating myelin processing, suggesting that therapeutic ... Access Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cordKarolina Kucharova1*, Yunchao Chang1,2, Andrej Boor3, Voon Wee Yong4 and William...
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báo cáo hóa học:" Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study" pptx
... [31-33]. Furthermore, hepatic lipase and Starexpression can be modulated by insulin [34,35] and lep-tin [34,36]. The hyperinsulinemia/insulin-resistance of the obese LY mice may contribute to the elevated ... hyperinsulinemia/insulin resist-ance [37]. Moreover, leptin bi-phasically modulatesgranulosa cell Star expression [36].An interesting and unexpected finding was the reciprocalshift in Hsd11b1 ... enhanced in obese rat [41] and human [39] adipose tissue, but reduced in liver. Anincrease in type 1 and a decrease in type 2 in the ovaries ofobese LY mice would predict an overall increase in ovar-ian...
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báo cáo hóa học:" HIV-related restrictions on entry, residence and stay in the WHO European Region: a survey" ppt
... factchecked the changes. SM fully reviewed and edited the next draft. JVL and MW addressed the reviewer’s comments. All authors read and approved the final manuscript.Competing interests The authors ... HIV-related travel restrictions. In these cases, we contactedfocal points and NGOs, receiving replies from everycountry except Israel. The resulting information and our initial review of th ehivtravel.org ... determine whetherthere were any HIV-related travel restrictions due to a lack of information.Conclusions: In 32% of the countries in the European Region, either there are some kind of HIV-related...
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báo cáo hóa học: " Neuro-Inflammation, Blood-Brain Barrier, Seizures and Autism" pot
... dysfunction and inflammation appear to alter BBB integrity [43,44]. Recent evidence indicates that the integrity of the BBB, especially leukocyte endothelial adhesion may also be involved in the ... mtDNA, TNF and VEGF), some of which increase the expression of vascular endothelial cell adhesion molecules (VCAMs) and permit exit of circulating lymphocytes in the brain. Focal brain inflammation ... as well as in inflammation [26]. Substances originating in the gut or the brain can trigger mast cells to release mediators that could disrupt the gut-blood barrier and blood-brain barrier...
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báo cáo hóa học:" Caveolin-1 enhances resveratrol-mediated cytotoxicity and transport in a hepatocellular carcinoma model" docx
... mechanism, in thisregard, is the presence of scaffolding domain in caveolin-1 that binds to and inhibits the activity of several signalingproteins in vitro and in situ, including the EGF and Neureceptors, ... purposes)advises on the work and helped with the interpretation of the data, WYF, AW, EW and DFS supervised all the work and wrote the paper together with HLY and MFM. Allauthors read and approved the final ... signal-regulated kinase (ERK), endothelialnitric-oxide synthase, threonine protein kinase, serineprotein kinase such as Src family TK, PKCα, H-Ras via the CAV1 scaffolding domain that combines with these...
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báo cáo hóa học: " e differential mediating effects of pain and depression on the physical and mental dimension of quality of life in Hong Kong Chinese adults" pptx
... allow us to infer causality. Cautions should be exer-cised when interpreting and generalizing the currentfindings in other populations as the present sample con-sisted of mainly Chinese female ... manuscript; RF participated in editing the manuscript.All authors read and approved the final manuscript.Competing interests The authors declare that they have no competing interests.Received: 20 ... findings offerinsights to the current understanding on the pain-depression relationship that whether pain and depres-sion be a predictor or mediator in impacting QoL isdependant on the specific...
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báo cáo hóa học: " Application of a hybrid wavelet feature selection method in the design of a self-paced brain interface system" pptx
... training and testing the classifierusing only the feature with the highest MI score, and thencalculated the fitness. Then we added features one at atime (according to their MI scores) and ... subject, IC and NC epochs were randomized and divided into train-ing, validation and test sets. The training set was used totrain the classifier, and the validation set was used to select the best ... crossover and uniform mutation. The sizes of the initial population and the population in the next generations were chosen as100 and 50, respectively. We used random initializationto initialize the...
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báo cáo hóa học: " Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury." pot
... IL-18 production in murine brains within 24hours. In contrast, the intracerebral injection of murineIntracerebral IL-18 concentrations in mice, as determined by ELISA in murine brain homogenates ... expression and posttraumatic regulation in the injured brain[3,12,13]. However, the TNF-dependent regulation of IL-18 in the injured brain has not yet been investigated. Wesought to determine the interrelationship ... ≤ 8) and indication for intra-ventricular catheters for cerebrospinal fluid (CSF) drain-age due to increased intracranial pressure (ICP > 15 mmHg) were included in this study. Drained CSF...
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báo cáo hóa học: " Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes" pdf
... ofmonocytes and macrophages across the BBB to the sites ofaxonal injury in the brain [33,37]. Both in vitro and in vivofindings suggest that hypoxia/ischemia-induced infiltra-tion of monocytes and ... important role in the initiation and propagation of hypoxia/ischemia-induced inflammation by secretinginflammatory chemokines that attract neutrophils and monocytes into the brain. However, triggers ... cytokines and chemokines during hypoxia;whereas NFκB is mainly involved in transcriptional regu-lation of these genes during the phase of reoxygenation[8,40]. The temporal interplay of these...
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Báo cáo hóa học: " A pandemic strain of calicivirus threatens rabbit industries in the Americas" doc
... responsible. The mostrecent of these occurred in June of 2005 in the state ofIndiana. Other outbreaks in the Americas include Mexico in 1988 and more recently, in 2004, Uruguay and Cuba.As with other ... bereplacing the original RHDV serotype in Europe [37] and an original RHDV strain from China in 1984 (WX84China, Figures 2 and 4) does not carry the RHDVa epitopewhile later isolates employed in ... rabbits in the Netherlands and has been suggested as a possible reasonfor the recent decline in free living O. cuniculus rabbits in that country [41]. These combined observations confirmthat the...
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