... may lead to continued growth andincreased malignancy. In many malignancies, the signaltransducer and activator of transcription 3 (STAT-3) plays an integral role in modulating oncogenesis, inhibitingapoptosis, ... Maleci A, La Sala A, Lande R, Ausiello CM: Defectiveexpression of interferon-gamma, granulocyte-macrophagecolony-stimulating factor, tumor necrosis factor alpha, andinterleukin-6 in activated ... 2005, 11:1314-1321.16. Matsukawa A, Kudo S, Maeda T, Numata K, Watanabe H, Takeda K,Akira S, Ito T: Stat3 in resident macrophages as a repressorprotein of inflammatory response. J Immunol...