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báo cáo hóa học: " Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment" ppt

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Báo cáo hóa học: "Investigating the synchronization of hippocampal neural network in response to acute nicotine exposure" pdf

... treatment of this disease with the use of nicotine,clozapine and the potential place of the new alpha7 nico-tinic receptor agonists [39,40].In this paper, we focus only on the influence of nicotineexposure ... Department of Bioengineering, Fulton School of Engineering ASU, Tempe AZ, USAFull list of author information is available at the end of the articleAkkurt et al. Journal of NeuroEngineering and Rehabilitation ... investigated. The hippocampal γ oscillations have been generated in response to the 100 Hz stimulus and isolated using the visual inspection and spectral analysis method. Our central hypothesis is that...
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báo cáo hóa học: "Single-trial classification of NIRS signals during emotional induction tasks: towards a corporeal machine interface" pptx

... asymmetry of signal val-ues around its mean relative to a normal distribution.6. Kurtosis: measure of the degree of peakedness of adistribution of signal values relative to a normal distri-bution.7. ... derived activations and should not be discarded.Regardless of the classifier of interest, time-domain fea-tures, i.e. either one of skewness or mean of Δ[HbO] and Δ[Hb], were consistently selected ... tissue oxygenation can be monitored. ANIRS instrument consists of light sources by which a tis-sue volume of interest is irradiated, and detectors thatreceive light after its interaction with...
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Báo cáo khoa học: "Corpus-Based Induction of Syntactic Structure: Models of Dependency and Constituency" pdf

... representation is isomorphic (in terms of stronggenerative capacity) to a restricted form of phrasestructure grammar, where the set of terminals and nonterminals is identical, and every rule is of theform ... way, often using standard is worth noting that these totally unsupervised num-bers are better than the performance of the CCMmodel of Klein and Manning (2002) running off of Penn treebank word ... se-quence is even a well-formed notion). For exam-ple, it is easy enough to discover that DET N and DET ADJ N are similar and that V PREP DET and V PREP DET ADJ are similar, but it is much lessclear...
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báo cáo hóa học:" Anti-angiogenic effect of high doses of ascorbic acid" pptx

... high-concentrations of AA (post intravenousadministration of 15 g, 30 g, and 60 g) and time of expo-sure were established. The infusion of 15 g of ascorbic acidin 45 min raised the plasma level of AA to ... possible mechanism by which high doses of AA may affect angiogenesis, we analyzed the effect of nitric oxide on the process of angiogenesis and the effect of high doses of AA on the level of NO in ... determine the effects of the high doses of AA on process of angiogenesis. Ang-iogenesis is the process of new blood vessel formationoccurring in both normal and cancerous tissues. To makenew...
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báo cáo hóa học:" In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells" docx

... generation.The vaccine administrated to this HCC patient is fusions of autologous whole HCC cells and DCs; therefore, con-cern exists regarding the possible induction of hepatitis bythis vaccination. However, ... Treg and inhibited CTL induction in the presence of HCCsp.Importantly, up-regulation of MHC class II, CD80, and CD83 on DCs was observed in the patient with advanced HCC after vaccination with ... dis-played a characteristic phenotype with increased expres-sion of HLA-DR, CD80, and CD83, as compared with thatobtained before vaccination (Figure 5A and 5B). Beforevaccination, 44.8 and...
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báo cáo hóa học:" Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool" potx

... harmonization of immune monitoring in clinicaltrials: quo vadis? Cancer Immunol Immunother 2008, 57:285-288.5. Janetzki S, Cox JH, Oden N, Ferrari G: Standardization and vali-dation issues of the ELISPOT ... analysis of cytokine gene expres-sion requires adequate infrastructure, initial antigen stim-ulation and safe storage and transportation of test probescan be performed with minimal equipment and ... Research and Hospital Management, Dept. of Biomedicine, University Hospital of Basel, Basel, Switzerland and 2Personnel Medical Service, University Hospital of Basel, Basel, SwitzerlandEmail:...
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báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot

... represent amarker of early activation of mesenchymal HSCs. Thisinterpretation is strengthened by the findings of a negativecorrelation of serum TGF-β1 with fibrosis score, feature of stable collagen ... proliferation and prevents apoptosis of HSCs [4].There is an increasing body of evidence that iron overload is associated with metabolic syndrome (MS) and NAFLD[5]. Observation of liver fibrosis in ... BMI, not normally distributed (P= 0.003), and ordinals, i.e., US and histology scores, wereexpressed as median and range.The t test or ANOVA and the Mann-Withey test or Kruskal-Wallis were...
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báo cáo hóa học:" Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells" docx

... (CC). We thank Guofeng Zhang of the Lab-oratory of Bioengineering and Physical Science (NIBIB) and Yide Mi of the Radiology and Imaging Sciences Program (CC) for technical assistance. We thank ... Daniel Glen and Rick Reynolds of the Scientific and Statistical Com-puting Core (National Institute of Mental Health [NIMH]) for their assist-ance during our use of the Analysis of Functional ... Institutes of Health, Bethesda, Maryland 20892, USA and 8Division of Biologic Drug Products, Office of Oncology Products, Center for Drug Evaluation and Research, U.S. Food & Drug Administration,...
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báo cáo hóa học:" Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation" docx

... for transduction of pDC.Immunophenotype of transduced pDCFigure 3Immunophenotype of transduced pDC. Comparative phenotypes of transduced and untransduced GEN2.2 in absence of maturation agent, ... these cells are BDCA2 and BDCA4(type II C lectin)-positive and CD11c- and CD1a-negative.Trypan blue exclusion and cell counting of LV and rAAVtransduced GEN2.2 at the end of the culture period ... Overlay histograms show the expression of relevant antigens for transduced GEN2.2 cultured without CpG (thin line), with CpG (thick line) and with CpG and gated on E-GFP+ (green line) versus isotype-matched...
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báo cáo hóa học:" Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs" pot

... DCTs and DCTIs have anoptimal antigen uptake capacity and upregulation of CD86, CD40 and class I, but low levels of CD83, as is expected of non-terminally mature DCs. The phenotypicprofile of ... alone or with class II cognate help (p766 and p672, phase II of thestudy; n = 6; Figure 1B). Peptides p766 and p672 areknown to be promiscuous[52]. Table 1 shows the HLAclass II profiles of the ... thathTERT p540 is not expressed or is cryptic on the surface of tumour cells and that immunization of cancer patients with hTERT p540 leads to the production of T cells that do not recognize tumour...
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