báo cáo hóa học: " Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcription" pptx
báo cáo hóa học: " Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcription" pptx
... purposes)Journal of NeuroinflammationOpen AccessResearch Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcriptionMichiyo ... indicate that curcumin potently inhibits MIP-2 production at the level of gene transcription and offer further support for its potential usein the treatment of inflammatory conditions of the ... MIP-2 production at the level of gene transcription and offerfurther support for its potential use in the treatment of inflammatory conditions of the CNS.Published: 25 February 2005Journal of...
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báo cáo hóa học: " Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures" pot
... correlated withHMGB1, IL-10, and IFN-g levels.DiscussionThis is the first study demonstrating a significant ele-vation of HMGB1 in the serum of febrile seizurepatients. Moreover, serum levels ... of children.AcknowledgementsThis research was supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (800-20110174), the ... patients and were also higherin patients without a family history of febrile seizuresthan in patients with family history. These findings mayreflect compensatory activation of anti-inflammatory...
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Báo cáo hóa học: " Transient expression of homologous hairpin RNA interferes with PVY transmission by aphids" docx
... between the sense and the antisense orienta-tions of the PVY CP sequence. We took advantage of the positive selection conferred by this prokaryotic resistance gene to reduce the risk of intramolecular ... exper-iments) that had been agroinfiltrated with the IRCPPVYconstruct were free of symptoms until their life cycles werecompleted. Dot blot analysis confirmed the visual obser-vations of the accumulation ... aimed at protecting crops against virus diseases [9].Aphid transmission is the main method of spread formost plant viruses in nature including members of the genus Potyvirus, the largest group of...
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Báo cáo hóa học: " Zenithal alignment of liquid crystal on homeotropic polyimide film irradiated by ion beam" pdf
... the roughness of the surface in the case of parallel irradiation is bigger than that that of the perpendicular irradiation case. Note that this matches well to other ion beam treatment results ... > , then the solid prefers the vapor to the liquid; however, since the liquid is heavier than the vapor, the liquid is placed under the vapor, and then, the solid is wetted partially by the ... structure of the polyimide AL-00010. In general, the pretilt angle of LCs is determined mainly by the chemical property of the side chain in the polyimide. Since the side chain in the AL-00010...
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Báo cáo hóa học: " Nanomechanical properties of a-synuclein amyloid fibrils: a comparative study by nanoindentation, harmonic force microscopy, and Peakforce QNM" potx
... The algorithm anal yzes both the forcecurve and the r2curve to accurately determine the point -of- contact, that is, the separation at which the tipstarts indenting the fibril. This point is ... (keff,representing the slope of the force curves in A) as a function of the stiffness of the sample. From the slope of this curve it is clear that the maximum sensitivity is achieved when both ... imaging. This phase signal is related to energy dis-sipation, which is determined by the viscoelastic andadhesive properties of the sample [21,23]. However,because of the convolution of multiple...
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báo cáo hóa học:" Adjuvant therapy of melanoma with interferon: lessons of the past decade" pot
... fact,after the publication of the results of LDI treatment inlow-intermediate-risk stage II melanoma patients, theydemonstrated the existence of a subset of responsivepatients [35] defined on the ... earlier or later changes in cytokine con-centrations might correlate with RFS. Of great interest,these data from the University of Pittsburgh show thatpretreatment levels of the proinflammatory ... suchcorrelation existed between these pro -inflammatory cytokines and the outcome of patients treated with the GMK vaccine. In fact, melanoma patients with the highestlevels of these cytokines had the...
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báo cáo hóa học:" High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia" pot
... in the AMLproteome between cytogenetic groups of this disease.They postulated, that analysis of the post-translationalmodifications could be useful to distinguish different sub-groups of ... two-dimensional patterns of patient AFigure 2Detail of the two-dimensional patterns of patient A. Detail of the two-dimensional patterns of patient A. Different expression of spot 19 (annexin 6) in the ... breast cancer a hypermethylation of the CpGisland of the σ gene was found that leads to gene silencingand absence of 14-3-3σ. The authors conclude, that the loss of σ expression contributes...
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báo cáo hóa học:" Heterogeneous activation of the TGFβ pathway in glioblastomas identified by gene expression-based classification using TGFβ-responsive genes" pptx
... indicate the outlier samples. The table underneath of the box plots are the summary statistics (count, mean, standard deviation (StdDev), median) of the expression level of SERPINE1 by gli-oma ... growth, survival and migration [4]. The impor-tance of activation of EGFR-PI3K/PTEN pathway in the pathogenesis of glioblastoma has been confirmed in the subgroup of patients who showed clinical ... computed using ANOVA is indicated at the top right corner of the plot. B. Significant association of SERPINE1 expression and the grade of the tumor. SERPINE1 is significantly upregulated in grade...
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báo cáo hóa học:" Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells" potx
... BPA at the 60 μMdose, whereas cyclin D1 which is known to modulate pro-liferation gets decreased. This scenario is reminiscent of acell cycle block regulated at the molecular level. At the same ... contribute to the toxicity of BPA. The regulation of caspase-dependentpathways of apoptosis suggests a specific action on the extrinsic and intrinsic pathways of apoptosis which is con-firmed by the ... regulated at the molecular level. Indeed, the fact that three different cell lines respond withapoptosis to BPA treatment and that this effect seems to bedose dependent indicates that this is...
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báo cáo hóa học:" Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma" doc
... has the fur-ther advantage of allowing the quantification of the methylation/demethylation ratio.Beside DNA methylation there exist other gene silencingmechanisms, such as the modification of ... linked to the methylation of the UCHL1 promoter DNA. This is fur-ther supported by the fact that a correlation between the methylation status of the CpG islet in the UCHL1 pro-moter DNA and the expression ... reflect the metastatic potential of RCC, but might alsomodulate the therapy sensitivity thereby influencing the treatment modalities of RCC patients. The function of UCHL1 in tumors is still...
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