... rapid depletion of circulating CD19+ Bcells and a suggestion of global B cell activation as evi-denced by significant upregulation of CD86 expression on B cells after infusion [14] (JR and RHV, ... major component of T cellhelp. Ligation of CD40 on DC, for example, inducesincreased surface expression of costimulatory and MHCmolecules, production of proinflammatory cytokines, and enhanced ... dual incubationwith CP-870,893 and CpG ODN 2006 compared to CpGODN 2006 alone induced higher expression of activationmarkers only for total B cells and CD27+ memory B cells and only for some,...