... where though intervention 3 was stilldominated by intervention 4 intervention 2 was no longerdominated by intervention 1. Instead intervention 2 hadan ICER of £6,036 (when compared to intervention ... stiffness, functioning;Model C: total WOMAC, total WOMAC2Model D: pain, stiffness, functioning, pain*stiffness,pain*functioning, stiffness*functioning, pain2, stiffness2,functioning2;Model ... reported in Table 3. Based onthe actual EQ-5D scores intervention 4 had both a highermean effect, and lower mean increase in cost, than inter-vention 3 – intervention 4 thereby dominated interven-tion...