... J, Sax M, Turano A & Chang CH (1982)Effects of structural variations in thiamin, its derivativesand analogues. Ann NY Acad Sci 378, 454–458.18 Dyda F, Furey W, Swaminathan S, Sax M, FarrenkopfB ... observations. Acta Crystallogr A3 4, 517–525.34 Vaguine AA, Richelle J & Wodak SJ (1999) sfcheck :a unified set of procedures for evaluating the quality ofmacromolecular structure-factor data and ... substrate.An alternative pathway for substrate activation isfavored by Baburina et al. [10–12] and Li et al. [13,14],who suggest that an activator molecule, bound to resi-due Cys221, is the starting...