Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot

Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot

Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot

... CyP's capacity to impair innate resistance to HSV-1 [56,57]. Further study is needed to test this hypothesis. Role of Stat 1 in innate resistance to HSV-1 The biological functions of IFN-α/β and ... Central Page 1 of 15 (page number not for citation purposes) Virology Journal Open Access Research Re-evaluating the role of natural killer cells in...
Ngày tải lên : 19/06/2014, 08:20
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

... designed on the basis of side-chain packing criteria from a modelled structure of the enzyme resulted in restor- ation of the energy of activation to the levels of the native enzyme and in an increased ... doi:10.1046/j.1432-1033.2002.02895.x strain TAB5. We particularly attempted to investigate the functional importance of the Gly pair, located in the vi...
Ngày tải lên : 22/02/2014, 04:20
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Báo cáo khoa học: "Examining the Role of Linguistic Knowledge Sources in the Automatic Identification and Classification of Reviews" doc

Báo cáo khoa học: "Examining the Role of Linguistic Knowledge Sources in the Automatic Identification and Classification of Reviews" doc

... number of test documents and find that the fea- ture vectors corresponding to some of these docu- ments (particularly the short ones) have all zeroes in them. In other words, none of the bigrams ... im- portantly, an analysis of these results show that the various types of features interact in an interesting manner, allowing us to draw conclusions that pro- vide ne...
Ngày tải lên : 17/03/2014, 04:20
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Báo cáo khoa học: Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site-directed mutagenesis potx

Báo cáo khoa học: Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site-directed mutagenesis potx

... with these mutations binding of NADPH was still too weak to allow determination of a K d value in the absence of the other substrate. In the presence of oxoglutarate, however, coenzyme binding ... NADH. Lysine is closer in size to the glutamate it replaces than arginine, and it is possible that the latter is too large to allow optimal orientation of the coenz...
Ngày tải lên : 30/03/2014, 03:20
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Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx

Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx

... with the histidine residue of the H-loop, and positions the ‘linchpin’ histidine in the correct orientation such that all atoms are then in position to favor abstraction of a proton from the attacking ... proteins. To answer this question, we took advantage of the trypsin-sensitive region situated in the linker domain of Abcb1a. Fol- lowing trapping in the...
Ngày tải lên : 07/03/2014, 06:20
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Báo cáo khoa học: Dissecting the role of the N-terminal metal-binding domains in activating the yeast copper ATPase in vivo pptx

Báo cáo khoa học: Dissecting the role of the N-terminal metal-binding domains in activating the yeast copper ATPase in vivo pptx

... FEBS Dissecting the role of the N-terminal metal-binding domains in activating the yeast copper ATPase in vivo Isabelle Morin 1,2,3, *, Simon Gudin 1,2,3 , Elisabeth Mintz 1,2,3 and Martine Cuillel 1,2,3 1 ... the N-terminus of Ccc2 is not only involved in receiving copper from Atx1, but also plays a crucial role in the overall function of the ATPase by deliverin...
Ngày tải lên : 23/03/2014, 05:22
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Báo cáo khoa học: Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability potx

Báo cáo khoa học: Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability potx

... unsure of the mechanism of DNA-induced stabilization of the protein, and whe- ther it is related to the normal RNA-binding function of coat protein, as RNA binding had no effect. The increased ... understood, and we have investigated these questions in this work. We sought to determine the role of protein–RNA and protein–protein interactions in virus stability,...
Ngày tải lên : 30/03/2014, 11:20
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Báo cáo khoa học: "Assessing the Role of Discourse References in Entailment Inference" pptx

Báo cáo khoa học: "Assessing the Role of Discourse References in Entailment Inference" pptx

... mandatory for inference. In another 28%, references could optionally support the inference of the hypothesis. In the remaining 28%, refer- ences did not contribute towards inference. The total ... enough; (3) the limitation to nominal coreference; and (4) overly simple integration of reference information into the inference engines. The goal of this paper is to ass...
Ngày tải lên : 30/03/2014, 21:20
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Báo cáo Y học: Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates pptx

Báo cáo Y học: Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates pptx

... it to the flavin ring through the S80 side-chain [22]. Such observation also suggested that in E301A FNR the side-chain of E139 might in uence the properties of the flavin, assuming some of the ... conformational chan- ges in the side-chain of another glutamic acid residue, E139, that in the mutant points towards the FAD cofactor in the active centre cavit...
Ngày tải lên : 31/03/2014, 08:20
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báo cáo hóa học:" A novel role of HLA class I in the pathology of medulloblastoma" docx

báo cáo hóa học:" A novel role of HLA class I in the pathology of medulloblastoma" docx

... of medulloblastoma cells in a wound scratch assay. DAOY cells were grown into near confluence when a wound was created in the center of the monolayer, and the ability of neighboring cells to migrate into the ... capability of medulloblastoma cells. In summary, we found a novel role of MHC class I con- tributing towards a more malignant phenotype of medul-...
Ngày tải lên : 18/06/2014, 15:20
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