Báo cáo sinh học: " Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA" ppt

... AccessResearch Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNABrian J Geiss1, Theodore C Pierson4 and Michael S Diamond*1,2,3Address: 1Departments of Medicine, ... established.The mode of introduction of siRNA affects the ability to establish RNAiBased on the timing experiments, the establishment of resistance to RNAi correlated with the onset of WNV ... RNAi resistance could be overcome by administra-tion of multiple inhibitory siRNA to disparate regions of the genome [35]. However, this was not observed withWNV, as simultaneous delivery of multiple...

báo cáo sinh học:" Incentives for retaining and motivating health workers in Pacific and Asian countries" ppt

... objectives of this paper are to: 1. Highlight the situation of health workers in Pacific and Asian countries to gain a betterunderstanding of the contributing factors to health worker motivation, dissatisfaction ... underlying factors for health workershortages, analysis of the determinants of health workerIntegrated strategies to tackle the inequitable distribution of doctorsFigure 12Integrated strategies to tackle ... improving the distribution of doctors to some extent, yet inequitable distribution persists and doctors usually stay for short periods in the rural hospitals. This is largely due to strong economic...

báo cáo sinh học:" Health worker densities and immunization coverage in Turkey: a panel data analysis" ppt

... during and after thecrisis. Indeed, this hypothesis is consistent with previousresearch from Turkey indicating that follow-up visits frommidwives are a determinant of vaccination rates [19].At ... estimatingequation:where Y is the rate of our composite EPI indicator and β1 is a (vector of) coefficient(s) relating to HRH density ineither aggregated or disaggregated form, i indexes ... proportion of childrenvaccinated against measles has been selected as one of theindicators of the fourth MDG. Rate of measles immuniza-tion is indicative of the coverage and quality of nationalhealth...

báo cáo sinh học:" Ageing medical workforce in Australia - where will the medical educators come from?" ppt

... for this age group in 2005. The number of specialists acting as medical educators is likely to remainunchanged or even increase due to the increasing number of specialists entering this age ... to the cohort aged 35-44 years in 2003. This is more than the numbers in thisage group in 2003.DiscussionThe results of this study show that 43% of general medicalpractitioners and 50% of ... in the following five years to 2010,and between 1700 and 2600 every five years after that to 2025. This amounted to a total of 11 722 retirees or 50% of the specialist workforce in the year 2000...

báo cáo sinh học:" Monitoring the newly qualified nurses in Sweden: the Longitudinal Analysis of Nursing Education (LANE) study" ppt

... 35. The Swedish National Higher Education Register: The national registry of educational statistics Stockholm: Statistical Databases of Sweden (SSD), Statistics Sweden; 1985. 36. Twisk JWR: Applied ... years of entering the profession [15,16,8,17]. Due to the problem of time lags being too short, involving a risk of missingthe phenomena entirely, a longer time lag was chosen,since the risk is ... atany of the 26 Swedish universities offering nursing pro-grammes in Sweden at that time (see Table 1). Lists of students were taken from the national registry of educa-tional statistics, comprising...

báo cáo sinh học:" Increasing health worker capacity through distance learning: a comprehensive review of programmes in Tanzania" ppt

... point to the advantages of distance learning to broaden access to training and to decrease costs. An MPHprogramme at the University of Western Cape in SouthAfrica provides degrees to health professionals ... support to study.Bureaucratic impediments inhibit effective planningand coordination of national distance learning programs.This is mainly due to the centralised structure of theCDE and lack of ... the variety of distance learning programmes that were a part of thisassessment.Additional findings included existence of political willfrom the government of Tanzania to implement distancelearning...

báo cáo sinh học:" Tanzanian lessons in using non-physician clinicians to scale up comprehensive emergency obstetric care in remote and rural areas" ppt

... at risk, and to encourage the health system to bemore responsive to the needs of the people [8]. One of its strategies is to upgrade health centres and use NPCs to improve accessibility to CEmOC ... forurgency to scale up the application of the concept of ‘task shifting’ with the use of NPCs for CEmOC servicesprovision and anaesthesia.List of abbreviationsAMO: assistant medical officer; ... trainees. This was jud ged to Table 1 Proportions of obstetric procedures performed during training by Assistant Medical Officers trained inComprehensive EmOCCategory of procedures Total number of proceduresperformedMinimum...

Báo cáo sinh học: " Kaposi''''s sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial ce" pptx

... induction of constitutive COX-2 expression and the resulting biosyn-thesis of PGE2 are sufficient to stimulate all of the key fea-tures of carcinogenesis including mutagenesis,mitogenesis, angiogenesis, ... theactivation of the COX-2 promoter.vGPCR-expression leads to increased PGE2 synthesisPGE2 synthesis is downstream of the cyclooxygenase con-version of arachidonic acid to PGH2. To determinewhether ... 95:13313-13318.29. Harris RE: Cyclooxygenase-2 (COX-2) and the Inflammogen-esis of Cancer. In Inflammation in the Pathogenesis of Chronic DiseasesVolume 42. Edited by: Harris RE. Netherlands ,...

Báo cáo sinh học: "The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program" doc

... to maintain the DC in an immature form. Thiscytokine stimulates proliferation of CD4+T cells, NKT,and cytotoxic CD8+Tcells,butnotTregs.IL-21enhances the production of a va riety of cytokines ... This receptor binds chemokines secreted by thetumor that serve as autocrine growth factors. In addition to transducing chemokines receptors to aid T cell traf-ficking to the tumor, investigators ... APCs, it is important to ensure that they are appro-priately HLA matched to the patient tissue.The investigator must also c onsider which population of responding cells is most appropriate to assay...

Báo cáo sinh học: "Research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech co" pdf

... pharmacology models are laid off or accept their severancepackages. Two recently published books may help to preserve this type of knowledge but much of this type of information is not in the public ... of companies to this issue and the repercus-sions of those actions for translational research in theindustry.Companies have consolidated through mergers andacquisitions resulting in lay-offs ... resulting in lay-offs for thousands of researchers and the closing of hundreds of laboratories to avoid perceived redundancies, focus on what is con-sidered to be more productive or lucrative...

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