Báo cáo hóa học: " Reliability and construct validity of the Participation in Life Activities Scale for children and adolescents with asthma: an instrument evaluation study" docx
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... pre-existing increased insulin resistance and dysfunction of beta cells. Insulin resistance is present in the acutely ill [13,15,18,28] in different intensity, but the factors determining the extent of ... insulin resistance byinducing the release of stress hormones. They also alterinsulin receptor signalling [12-16] and create insulinresistance. Due to these actions, glucose uptake in fat and muscle ... value in the Recommendations of the American Heart Association [35] and the trigger for initi-ation of insulin treatment for ICU patients recommendedby the American College of Endocrinology...
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Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx
... wasdiluted 1 : 20 and incubated for another 2 h at 27 °C, and then for 1 h at 37 °C. Bacteria were washed in NaCl ⁄ Pi and cells were infected with Yersinia at an MOI of 60 : 1 for the indicated time ... YpkA and RhoA interact in vitro and whether this protein complex includes OTUB1.YpkA was immunoprecipitated and the presence of OTUB1 and RhoA examined by immunoblotting(Fig. 6C). YpkA, OTUB1 and ... OTUB1-HAor the C91S mutant and after 24 h infected with Yersinia pseudotuberculosis (MOI 60 : 1) for 15, 30 and 60 min, followed by fixing and staining for extracellular bacteria using fluorescein isothiocyanate...
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Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx
... Lys169 in H1.4 and H1.5, or Lys170 in H1.3. In mouse, the H1.4variant has no modifications at Lys26, and at posi-tion 27 there is an alanine, rather than a serine [43].Ubiquitination and formylation For ... with growth rates [64] and can be significantly increased. The addition of compounds that in uence the cell cycle will causechanges in the levels of phosphorylation of the linkerhistone isoforms ... oncell growth rates and S. Lambert for his advice and assistance in the preparation of the chicken linker hi-stones. Both of the aforementioned are based in the School of Pharmacy and Biomolecular...
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Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx
... cDNA of Chang cells, and the PCR product was sequenced.(D) PCRs for exon 1 and exon 1a were performed in Huh7 and Chang cells. (E) The boundary regions of exon 8 and exon 9 in the genomicDNA of ... are stained cells on the bottom of the Matrigel-coated inserts. The number of invasive cells wasdetermined by counting the number of stained cells and then normalizing it to the number of control ... invasiveness.ResultsIdentification of the human occludin splicevariantWe detected a splice variant of occludin in liver celllines by using an antibody to the occludin N-terminus,which detected two specific bands, one of...
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Báo cáo khoa học: Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor jB1 and mitogen-activated protein kinase pathways doc
... gels and transferred to PVDFmembranes. To control the complete and even transfer of proteins to the blotting membranes, membranes wereimmersed in a Ponceau Red-containing solution and the stained ... Recent advances indi-cate a number of links between the activation of p38kinase and the DNA checkpoint pathways and theirpossible interaction in the modulation of cell cycle con-trol and DNA ... per-centages of the cells in the G0 ⁄ G1, S and G2 ⁄ M phases of the cellcycle after treatment with 20 lM or 100 lM ATP for 24 h. The gat-ing used for the quantification of the cells in the G0 ⁄...
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Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... H128P,PigE17DCPT1B and HumanD17ECPT1B, and from 0 to500 lm for D 18PigCPT1B and D28PigCPT1B). The assaywas performed at 1 mm carnitine as standard. To analyzePigE17DCPT1B and HumanD17ECPT1B mutants, the assay ... Substitution of glutamate-3 valine-19leucine-23 and serine-24 with alanine in the N-terminalregion of human heart muscle carnitine palmitoyltrans-ferase I abolishes malonyl CoA inhibition and binding.Arch ... Roles of the N- and C-terminal domains of car-nitine palmitoyltransferase I isoforms in malonyl-CoAsensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved...
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Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx
... movement and the ques-tion of whether binding of a single substrate to one of the two domains can also stabilize the structure of the other domain [32–34]. Often the results of studies with the solubilized ... 3-PG and MgADP together in the other case [76] caused merging of the two transitions into a single one. This indicatesincreased domain cooperativity upon substrate binding in the mutants. Another ... (e) and W333 (n) yeast PGKs were determined at the scanning rate of 1.0 KÆmin)1, in the absence of substrates (A, B) and in the presence of 10 mM 3-PG (C, D). In (A) and (C) the values of excess...
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Báo cáo khoa học: Acute intermittent porphyria – impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties pdf
... amino acids are indicated in red; and the position of the last amino acid before the frameshift is shown in black. The interacting partners of the mutated residues are shown in yellow and the ... dipyrromethane (DPM) cofactor is shown in the ball and stick representation. Magenta indicates the beginning and the end of the region coded by exon 12. The N- and C-termini arelabeled N and C, ... structure of human HMBS indicating the positions of the mutations observed in the patients. The N-, central and C-domains are shown in silver, blue and green, respectively; the positions of the mutated...
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Báo cáo khoa học: Lipid-induced conformational transition of the amyloid core fragment Ab(28–35) and its A30G and A30I mutants docx
... that the binding of the amyloidprotein of AD to lipid membranes can change theirfluidity [34]. Therefore, we examined the effect of bind-ing of the WT, A30G and A30I peptides on the fluid-ity of ... self-association and to measure distanceswithin proteins and other macromolecules [35]. In order to understand the folding and unfolding of peptides, both in the presence and the absence of PGlipids, ... propensities, and side-chain–side-chain and side-chain–backbone interactions. This study also gives an understanding of the specific role played by hydro-phobic residues in membrane lipid binding and can...
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Báo cáo khoa học: Translation initiation region dependency of translation initiation in Escherichia coli by IF1 and kasugamycin pdf
... the determinants of this effect, as they could reveal interactions between the factor and the rest of the translation initiationmachinery in the growing cell. Comparison of severalmutants with ... kasugamy-cin-binding site on the 30S subunit or on the 70S ribo-some in the region of the mRNA-binding tunnel in the E-site and P-site [32,33]. As no effect of kasugamycinon mRNA binding to the 30S ... determined for the 2A¢ and 3A¢ gel bands, and compared with the isotoperatios of the total cellular protein, from the sampletaken before the purification step. As can be seen in Fig. 1, values for...
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Từ khóa: update of the k doqi clinical practice guideline for diabetes and chronic kidney diseasebáo cáo môn học hóa dầubáo cáo trường học văn hóa năm 2012báo cáo trường học văn hóaquảng cáo trên báo giấy hoa học tròtrang bìa báo cáo đại học hoa senNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngThơ nôm tứ tuyệt trào phúng hồ xuân hươngGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ