báo cáo hóa học: " Measurement properties of the Brazilian version of the Pediatric Quality of Life Inventory (PedsQL™) cancer module scale" pdf
Báo cáo khoa học: Ibuprofen binding to secondary sites allosterically modulates the spectroscopic and catalytic properties of human serum heme–albumin doc
... 10)1s)1).Ibuprofen binding to tHSA–heme-Fe(II)-NOFigure 4 shows the binding isotherm for ibuprofenbinding to tHSA–heme-Fe(II)-NO. Analysis of the dependence of the molar fraction of the ibuprofen-bound ... indicates that the removal of domain I from HSA does not significantlyaffect the functional and structural properties of domains I and II [i.e. of the 1–382 region of (t)HSA].l The values of the Hill ... kþoffð7Þwhere koff(2)and koff(3)indicate values of koffoccurring atK2< [ibuprofen] < K3, and at K2< K3< [ibuprofen],respectively, and kþoffis the koffvalue obtained in the absence...
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Báo cáo khoa học: Physicochemical properties and distinct DNA binding capacity of the repressor of temperate Staphylococcus aureus phage /11 doc
... regu-late the transcription of genes located on the two sides of the /11 cI-cro intergenic region. Furthermore, the information gathered in the present study may proveuseful in the construction of ... homol-ogy over the entire length of the k repressor. Interest-ingly, although the sequences of the C-terminal ends of the above S. aureus phage repressors are identical, the sequences of their N-terminal ... majorgroove of the DNA helix [1]. Therefore, the data alsosuggest that the interaction between CI and the opera-tor DNA may occur through the major groove of the operator DNA helix. The absence of detectable...
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Báo cáo khóa học: Structural properties of the protein SV-IV potx
... identified by the massincrease of 42 mass units. The relative level of acetylation of a peptide was estimated on the basis of the intensity ratio of the native and acetylated species. From the data ... a-helix in the whole protein, and the 1–70region is poorly structured.SDS increases the a-helix content of proteins revealing the helical potential. The a-helix content of the monomericform of SV-IV ... structuralfeatures of both forms.Lysine acetylation gave us further information about the structural environment of the lysines, as acetylated lysinescan be considered to be exposed to the surface of the protein,...
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Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc
... the site of interaction with AKAP proteins [5,6]. The symmetry axis of the dimer is along the y-axis shown in the Figure. Figure 4Bshows the van der Waals model of the top face of the beststructure ... A further rotation of the orientation of RIIaD/D of Fig. 4B by 180° about the x-axis shows the bottomface of RIIa D/D (Fig. 4C). There is some hydrophobiccharacter in the bottom face of RIIa ... bar at the C-terminus of eachhelix corresponds to the variable helical range within the ensemble of the 24 structures. There is no variation at amino terminus of each helix. The sequence of ionizable...
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Báo cáo khoa học: Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant Mark Wehner and Christian Herrmann doc
... con-served in the primary structure of the GTPase domain of hGBP5, so the formation of GMP must be impairedin an as yet unknown manner. Sequence alignments of the large GTP-binding domains of hGBP1, ... for the lack of GMP formation(see Fig. S2). The similar hydrolytic activities of the a ⁄ b and C-terminally truncated forms of hGBP5 are incontrast to that of the analogous deletion mutant of hGBP1 ... account). The size of the protein complex is onlyslightly increased when nucleotide-free or in the presence of GTP. As with hGBP5ta, the complex isincreased to the size of a tetramer after binding of GppNHp,...
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Báo cáo khóa học: Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus A member of a novel protein family related to protein disulfide-isomerase doc
... of the PDI [42], and t hat this site is far away from the redox active sites in the sequ ence. Furthermore, the measurements of the rates of PDI-catalysed refolding of scrambled RNase A, in the ... (225 mM)9:1(25 mM). At the end of the incubation, 40 lL of the mixturewas added to each of the five solutions; these were then leftto react on ice for 5 min. The reaction mixtures w ereanalysed ... of the active site in the N-unit. As regards the oxidative activity, the two units alsodisplay differences in their functional properties, with the site at the C-termus always predominant, the...
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Báo cáo khoa học: Conformational properties of bacterial DnaK and yeast mitochondrial Hsp70 Role of the divergent C-terminal a-helical subdomain pdf
... that of DnaK. The twofold reduction of the KSVvalues estimated formtHsp70 both in the absence and the presence of ATP(Table 2) supports the existence of differences in the Trp environment of ... that the lid did notclose tightly the binding site of these chimeras. Thus,this finding indicates that the interaction of mtHsp70PBD with the DnaK ATPase domain modifies the accessibility of the ... Replacement of the complete a-helicaldomain in KKCC resulted in disappearance of the intermediate endotherm, which was assigned to the PBD. In contrast to what was observed for the otherproteins, the...
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Báo cáo khoa học: Enzymatic properties of the lactate dehydrogenase enzyme from Plasmodium falciparum pdf
... polarity of the environment of the fluorophore. In the case of PfLDH, the signal changeon binding to the active site was too small to be usedas a reliable reporter of the formation of the binarycomplex. ... the rate of the conformationalchange, k3H the hydride transfer and k4 the rate of the product-off step. Hence, in these circumstances, the steady-state KMis expected to be smaller than the apparent ... the binding of pyru-vate to the E–NADH complex is a rapid equilibriumprocess, then the measured KM(KM¢) in the single-turnover reaction is simply equal to the Kdfor the for-mation of...
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Báo cáo khoa học: Physical properties and surface activity of surfactant-like membranes containing the cationic and hydrophobic peptide KL4 potx
... sys-tems showed the end of the melting process at 41 °C. The decrease of the Tmin PA-containing vesicles isexplained by the partial extraction of PA from the bilay-er by the formation of PA ⁄ Ca2+complexes. ... bilayers, and theirdependence on calcium. Therefore, the objectives of this study were to analyze (a) the effect of KL4on the physical properties of membranes, in the absence andpresence of Ca2+, ... probablyinvolved the extraction of PA from the bilayer at con-centrations of > 100 lm calcium. Thus, the formation of PA–Ca2+complexes might explain the decrease of the Tm of PA-containing...
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Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"
... for lifestyle. The total score was thirty-seven. Lifestyle Q1 to Lifestyle Q3 were equally weighted and represented 81% of the total value of the questions, whereas, Lifestyle Q4 and Lifestyle ... conditions, and then to specify the name of that con-dition. If the participant failed to indicate the name of the condition regardless of a “yes”, the survey was discarded assuming the participant ... extremes of the emotional spectrum were shown. At the end of the videos, the brachial artery constricted for five minutes and was then released. In fourteen of the twenty volunteers the artery...
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Từ khóa: Báo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDETrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam