... Taichung, Taiwan The goal of this study was to relate conformational changesin the N-terminal domain of chicken troponin I (TnI) to Ca2+activation of the actin–myosin interaction. The twocysteine ... the formation of a binary complex with TnC. This result is consistent with the notion that the antiparallel arrangement of TnI andTnC would lead to a more elongated configuration of the troponin ... (1997)Interaction of the second binding region of troponin I with the regulatory domain of skeletal muscle troponin C as determined byNMR spectroscopy. J. Biol. Chem. 272, 28494.5.McKay,R.T.,Pearlstone,J.R.,Corson,D.C.,Gagne,S.M.,Smillie,...