báo cáo hóa học: " Development of the Knee Quality of Life (KQoL-26) 26-item questionnaire: data quality, reliability, validity and responsiveness" pptx

... 0.05).Discussion The present work shows the use of the regulatorysequences of the H19 gene for the development of DNA-based therapy for human ovarian cancer related ascites. The successful development of ... μg of Luc -H19 or the LucSV40 plasmid. The values represent the luciferase activity of the H19 promoter relative to the activity of the control vector LucSV40. B. The killing potential of the ... normal tissues, and thusmay help reduce tumor burden, fluid accumulation;improve the quality of life of the patient; and prolongtheir life span. This suggested approach was further dem-onstrated...

... cells[16-18]. The activities of IL21 have been shown to behighly dependent on the lineage of the target cell, the activation state of the target cell and the presence of otherco-stimulators and immune ... analyzed the data and co-wrote the manuscript. SJ and AAW performed all the pilot studiesin humans and monkeys that identified the candidate biomarkers, and theyparticipated in the data analyses. ... Ab-01 and control Ig and analyzed the data, and KA and SAperformed the experiments on monkeys dosed in vivo with Ab-01 or IgG1TM.ERL performed data analysis and review and participated in the...

... ISH and the expression levels of IGF2-P4 and H19 transcripts were determined by the intensity of the hybridization signal and by the quantity of the stainedcells. Table 3 shows that out of 28 ... early studies of our group and others, the transcriptional regulatory sequences of the H19 and IGF2genes emerged as candidates for cancer targe ted therapy.H19 and IGF2 (the human P3 and P4 promoters) ... cycles of 94°C for 30 sec, 59°C for45 sec and 72°C for 60 sec, and finally 72°C for 5 min. The PCR reactions were carried out in 25 μlvolumesinthepresenceof6ng/μl of each of the forward and the reverse...

... levels of impaired activities, symptoms, and poorer quality of life for the COPD sample and greaterlevels of impaired activities, symptoms, social function-ing, and poorer quality of life scores ... measures and extend our understanding of the impact of respiratorydisease symptoms on sleep impact and quality. Given the prevalence of sleep problems in patients withasthma or COPD and the absence ... coordination; data collec-tion; data oversight; and reporting of data. DMMmanaged the UK portion of the research study, includingdeveloping protocols; site coordination; data collection; data oversight;...

... and known group validity were also metwith the exception of the domain of Daily Life (proven in an ad hoc analysis) as well as the 1/2 standard deviationthreshold for the MID.Conclusion: The ... generation in the development of two obesity-specific measures: the Obesity and Weight Loss Quality of Life (OWLQOL) Questionnaire and the Weight-Related SymptomMeasure (WRSM). Clin Ther 2002, ... al.: Development and validation of the Treatment Related Impact Measure of Weight (TRIM-Weight). Health and Quality of Life Outcomes 2010 8:19.Submit your next manuscript to BioMed Centraland...

... A measure of health-related quality of life and quality of life for patients with pulmonary hypertension. Qual Life Res 2006, 15:103-15.16. Rasch G: On general laws and the meaning of measurementinpsychology. ... manuscript. JB designed and managed the valu-ation survey, analysed and reported on the valuation data and contributed to the writing of the manuscript. Allauthors read and approved the final manuscript.Acknowledgements The ... the Rasch analyses) were candidates for exclusion. However,it was the aim to include a reasonable spread of items interms of the degree of severity they represented. The logitseverity of the...