... Smadbinding element (SBE) in the JunB promoter that acts as atransforming growth factor- b, activin, and bone morphogeneticprotein-inducible enhancer. J. Biol. Chem. 27 3, 21 145 21 1 52. 42. Dennler, ... assay 922 M. Lutz et al.(Eur. J. Biochem. 27 1) Ó FEBS 20 04 In contrast to TGF-b signaling through receptor serine/threonine kinases, nerve growth factor (NGF) signals via atyrosine kinase receptor ... multiple signaling cas-cades originating from other receptor systems are involved in modulating Smad signaling [14 ,27 ,30,51, 52] . In thepresent work, we demonstrate that in PC 12 cells NGF-stimulated...