... Access Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model Linda Petrone1, Maria G Ammendolia2, ... al.: Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model. Journalof Translational Medicine ... (IgG1, Ig G2 b, IgG2c and IgG3).Antigen-antibody complexes were detected using the fol-lowing HRP-secondary antibodies (Sigma-Aldrich): rabbitanti-mouse IgG (H+L), goat anti-mouse IgM (μ-chain),goat...