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Báo cáo sinh học: "Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18" potx

Báo cáo sinh học:

Báo cáo sinh học: "Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18" potx

... 9:59http://www.translational-medicine.com/content/9/1/59Page 9 of 11RESEARC H Open AccessResveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18Clarisa ... as: Salado et al.: Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18. Journal of Translational Medicine 2011 9:59.Submit ... regulates melanoma metastasis occur-rence via VLA-4-dependent B16M cell adhesion to HSE, the effects of RVL on IL-18 secretion and VCAM-1expression by hepatic sinusoidal cells, and on the cancercell...
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Báo cáo khoa học: Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma pot

Báo cáo khoa học: Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma pot

... revealedthat over-expression of the three proteins was signifi-cantly associated with the genesis and progression of CRC. The functional implications of the alterations in the levels of these proteins are ... S100A9 and LASP-1 may play animportant role in the development and progression of CRC. Further functional and clinical analysis of the proteins is necessary to elucidate their precise role in the ... uniform format was designed by the Ethics Committee and signed by the patients involvedin the study before the trial. All the patients understood the trial’s purpose and procedures.ProteomicsProteomics...
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Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

... (b) the role of the D to N mutation; and (c) the role of the sequence and length of the C-terminal extension.To address whether presence of extra residues at the N-terminal of Pfg27Awere responsible ... aggregate formation, and the cellmachinery gets rid of these aggregates by the combinedaction of chaperones and intracellular proteases [1–3].Several studies have shown that the nature of terminalresidues ... highlight the central issue that solubility of fusion proteins is not necessarily indicative of either properfolding or of increased solubility of the protein of interest.We propose that the success...
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báo cáo sinh học:

báo cáo sinh học:" Using nurses to identify HAART eligible patients in the Republic of Mozambique: results of a time series analysis" potx

... including the study site, the study month (a meas-ure of the effect of time), the number of monthly MD/MOvisits (a measure of MD/MO capacity), and the number of monthly new enrollees at the clinic ... into the HIV clinic, the dates of all clinical appoint-ments and CD4 tests and the dates of starting HAART.Outcome 1For the first outcome, the proportion of first visits to MD/MOs made by HAART-eligible ... HAART initiation).Further research is needed to address these aspects of the study and confirm the effect of the CD4 nurse interven-tion on clinic functioning and rate of HAART-eligiblepatients...
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báo cáo sinh học:

báo cáo sinh học:" Addressing gaps in surgical skills training by means of low-cost simulation at Muhimbili University in Tanzania" potx

... of the long saphenous vein on themselves, thenperform a venesection and insert the intravenous cannulainto the vein of the model and secure the cannula in place. The intubation station was carried ... donated by the University of California San Francisco (UCSF) GlobalHealth Sciences.Development and execution of the training required atotal of 290 work-hours (Table 2). The execution of the surgical ... read and approved the final manuscript.Acknowledgements The authors wish to thank the MUHAS Anatomy and Histology Depart-ment for allowing the use of their laboratory space to conduct the study....
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báo cáo sinh học:" Scaling up proven public health interventions through a locally owned and sustained leadership development programme in rural Upper Egypt" ppt

... align and mobilize their teams and their stakeholders; and inspire each other. They learnedto manage their resources–to plan, organize and imple-ment act ivities and to monitor and evaluate theirresults ... of the health workers in Aswan and the results they haveachieved over six years have come to the attention of the centra l MOHP, and other governorates across Egyptare requesting the LDP for their ... participation in the LDP, the districts of Aswan, Daraw and Kom Omboincreased the number of new family planning visits by 36%, 68% and 20%, respectively. The number of prenatal and postpartum...
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báo cáo sinh học:

báo cáo sinh học:" A model linking clinical workforce skill mix planning to health and health care dynamics" pot

... [31,32]. The addition of the concept of 'Poli-cies, Governance and Power' explicitly links the scope of the dynamics of health and health care to the politicalprocess within and outside ... from the protein mole-cule to the cell to the organ to the body to the externalworld. Future management of health may involve pre-venting and managing the perturbation of these networks by disease ... output and subsequent out-come of the service provided by the clinical sector of the health system. The clinical workforce The clinical workforce of our concern is comprised prin-cipally of: ▪...
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báo cáo sinh học:

báo cáo sinh học:" Field Epidemiology Training Programmes in Africa - Where are the Graduates?" pptx

... investigation and management, and pro-duction and circulation of IDSR bulletins in Zimbabwe,Uganda, Kenya, the United Republic of Tanzania, and Ghana is the function of FETP graduates working within the ... tables and charts. The Kenya, Nigeria, South Africa, and the UnitedRepubli c of Tanzania FELTPs were excluded, as none of them had produced graduates for more than the 3-yearcutoff at the time of ... 8:18http://www.human-resources-health.com/content/8/1/18Page 3 of 7 and other developing regions of the world. On the otherhand, anecdotal evidence suggests that the majority of graduates of field epidemiolo gy training programmes(FETPs)inAfricastayontoworkintheirhomecoun-tries....
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báo cáo sinh học:

báo cáo sinh học:" Community-owned resource persons for malaria vector control: enabling factors and challenges in an operational programme in Dar es Salaam, United Republic of Tanzania" ppt

... relationship of the investigator with the CORPs, allowing the investigator to ob serve and under-stand the operational challenges faced by the CORPs and the program as a whole. Informal appraisal of theseobservations ... committees and workonly where they live. Furthermore, the recruitment pro-cess of the community personnel needs to critically con-sider the heterogeneity and mobility of the humanpopulation in the ... Supervisor)Some of the CORPs they have had previous experiences, withUNICEF or other projects, so they know how to approach people and inform them. Others are inexperienced and the moment theyrun...
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Báo cáo sinh học:

Báo cáo sinh học: "15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level" docx

... placed the 4 and 48 hour samples at the extremes with the other samples in between and closer to the 48 hour samples. This indicated that the two agents induced one group of genes at 4 hours and ... [15,17]. The ability of Granulysin to replicatesome GM-CSF-induced monocyte responses is shown by the observation that between 4 and 48 hours thou-sands of genes were induced by both GM-CSF- and Granulysin. ... GO analyses were made with DAVID. The bars in the GO analysis indicate-Log10 of the p-value of the overrepresentation of the induced genes for each GO family. The green bars indicate down-regulated...
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