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Báo cáo sinh học: "Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy" docx

Báo cáo sinh học:

Báo cáo sinh học: "Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy" docx

... YZ participated in nanoparticlecharacterization, DC imaging and data analysis. MO participated in nanoparticle characterization, DC loading and imaging and data analysis. MHparticipated in DC ... and loading, analysis of presentation of murine MHC class II-restricted peptides and murine non-classical MHC class I, Qa-1-restricted peptides encapsulated into nanoparticles, and data analysis. ... participated in the design of the study, helped with the statistical analysis and manuscript preparation. YZ participated in nanoparticle characterization, DCloading and imaging and data analysis....
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báo cáo hóa học:

báo cáo hóa học:" Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy" doc

... 2 of 10RESEARC H Open AccessEnhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapyWenxue ... TAA-derived peptides to human DC, and thedevelopment of nanopartic le s incorporating MHC class II and non-classical MHC class I, Qa-1-binding peptides that are able to stimulate helper CD4+ and cytotoxicCD8aa+TCRab+ ... cells also play an important part in the anti -tumor responses [15,16]. It is clear from our data that nanopar-ticles containing class Ib MHC (Qa-1 or HLA-E in humans) binding tumor- associated antigens...
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Báo cáo sinh học:

Báo cáo sinh học: " Unusual presentation of hepatitis B serological markers in an Amerindian community of Venezuela with a majority of occult cases" doc

... co-circulation of a wild type virus along with a variant harboring a premature stop codon at aa 42 of the core protein, and a variant exhibiting a deletion of 28 aas (aa 78–105) (Figure 3). A partial ... Domingo J Garzaro,Aff2 Email: dgarzaro@gmail.com Mar a C Duarte,Aff1 Email: mcarolad@hotmail.com Daisy M Garc a, Aff1 Email: mayilag@hotmail.com Milian C Pacheco,Aff1 Email: milianp@hotmail.com ... Amerindians populations were included, from the Orinoco Delta (DELTA), in Yucpas (JAPREIRA) and in Yanomamis (Y) and Piaroas (P) from the Amazon (AMAZ) Figure 3 HBV core variants circulating in...
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báo cáo hóa học:

báo cáo hóa học:" Increased vulnerability of rural children on antiretroviral therapy attending public health facilities in South Africa: a retrospective cohort study" docx

... were increasedlevels of unavailable baseline clinical and on-treatmentCD4 cell and viral load results at rural facilities. Unavail-able baseline clinical and immunological values werealso independently ... Africa.Improving clinical outcomes and increasing uptake of ARTPaediatric treatment is still provided mainly at hospitalsdue to the availability of paediatricians and related support and a shortage of ... providingrural ART in sub-Saharan Afr ica include a lack of healthpersonnel, lack of diagnostic facilities, difficulty and expense transporting medication to clinics, and a lack of staff training...
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Tài liệu Báo cáo khoa học: Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation pdf

Tài liệu Báo cáo khoa học: Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation pdf

... MPH a Forward: 5¢-TAGAATTCGCTGCTCCACAAGTTAGAACT-3¢Reverse: 5¢-TAGCGGCCGCTTACTTTGGGTTAACGACGGA-3¢Mutant MPHbG194P 5¢-CCTGACGATTCTAAACCGTTCTTCAAGGGTGCC-3¢G198P 5¢-AAAGGTTTCTTCAAGCCGGCCATGGCTTCCCTT-3¢G194P ... migrated as a single band, of 33 kDa apparent molecular mass, on SDS ⁄ PAGE(Fig. 4). Kinetic parameters of WT and mutant enzymeswere measured as described in the Materials and meth-ods, and the ... least three replicates. The Km and kcatval-ues were calculated by nonlinear regression using graphpadprism 5.0 (GraphPad Software Inc., La Jolla, CA, USA).Thermostability assay of WT and...
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Tài liệu Báo cáo khoa học: Enhanced expression of Mcm proteins in cancer cells derived from uterine cervix docx

Tài liệu Báo cáo khoa học: Enhanced expression of Mcm proteins in cancer cells derived from uterine cervix docx

... chromatin-bound proteins(Fig. 3 and Table 2). In contrast, the amounts of totalFig. 4. Abundance of Mcm2 mRNA in HeLa and WI-38 cells. (A) Total mRNA was purified from HeLa and WI-38 cells, and ... deep invasion. To furthercharacterize the expression of Mcm4, PCNA and Ki67 in cancer cells, a section that contains a boundary region of CIS (CIN3 of FIGO classification) and dysplasia (CIN1)was ... Sectionscontaining part of the boundary of CIS (left portion) and dysplasia(CIN1 of FIGO classification, right portion) were stained with HE,anti-Mcm4, anti-PCNA and anti-Ki67 Ig as indicated.1096...
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báo cáo sinh học:

báo cáo sinh học:" The role of regulation in influencing income-generating activities among public sector doctors in Peru" doc

... regulate teaching and clin-ical practice" (General medicine #3, private clinic).Income, quality of care and workforce planning werethree areas for regulation identified:"The principal ... degree of collective action over quality and the maintenance of professional reputations. Further researchinto this issue in rural areas is needed to ascertain the geographical generalizability of ... pro-vincial and hospital levels pertaining to the legality of such activities [4]; in Canada, there is some ambiguityabout the legal status of private practice per se across prov-inces [5]; and in Thailand,...
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báo cáo sinh học:

báo cáo sinh học:" The College of Medicine in the Republic of Malawi: towards sustainable staff development" docx

... Malawian staff already in place and the number of postgraduate trainees joining the COM.The way forwardClearly it will take many years before well trained and experienced Malawians can compete for ... return and it was felt that the medicaltraining received abroad was not appropriate for a doctorworking in an African setting [2]. The curriculum at theCOM was introduced in a gradual manner, and ... to a pre- and postgraduate train-ing programme of high standard, wholly owned and administered by well trained Malawian professionals.Competing interestsThe author(s) declare that they have...
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báo cáo sinh học:

báo cáo sinh học:" Nurses'''' experiences of recruitment and migration from developing countries: a phenomenological approach" pdf

... 2001,10(4):254-265.34. Charest CA: Analysis of a transcultural innovation: the social-isation of Filipino-graduate nurses into an acute health careorganisation in the United States. In Graduate School Volume ... nursing workforce in sub-Saharan Africa. In Issue Paper no 7 Geneva , International Council of Nurses; 2005. 29. Kline D: Push and pull factors in international migration. Jour-nal of Nursing ... DATH, and informed consent was obtained from all participants.Data analysis A 'bottom up' approach to coding [23] was used. Thisinvolved reading each interview transcript several times,then...
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báo cáo sinh học:

báo cáo sinh học:" Postoperative outcome of caesarean sections and other major emergency obstetric surgery by clinical officers and medical officers in Malawi" docx

... of America: measures of the African brain drain.Human Resources for Health 2004, 2:17.7. Fernando D, Jaya Tilleka A, Karunaratna V: Pregnancy-reducingmaternal deaths and disability in Sri Lanka ... AbstractBackground: Clinical officers perform much of major emergency surgery in Malawi, in theabsence of medical officers. The aim of this study was to validate the advantages and disadvantages of ... outcomes of their procedures are comparable to those of medical officers. Clinical officers constitute a crucial component of the health care team in Malawi for saving maternal and neonatal lives...
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