báo cáo hóa học: "Impact of gastroesophageal reflux disease on patients'''''''' daily lives: a European observational study in the primary care setting" doc
báo cáo hóa học: "Impact of gastroesophageal reflux disease on patients'''' daily lives: a European observational study in the primary care setting" doc
... gastroesophageal reflux disease (GERD) on the daily lives of patientsmanaged in primary care is not well known. We report the burden of GERD in a large population of patients managed in primary care, in ... disease. Conclusion The findings of this European observational study showthat a proportion of patients with GERD are inadequatelytreated, having clinically relevant impact on their daily lives. These data ... preparation. Data analysis was provided by Astra-Zeneca. All authors read and approved the finalsubmission.Additional materialAcknowledgementsThis study was supported by AstraZeneca. We thank...
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báo cáo hóa học: " Impact of gastroesophageal reflux disease on work absenteeism, presenteeism and productivity in daily life: a European observational study" doc
... employee of AstraZeneca.Authors' contributionsAll authors were involved in data interpretation and man-uscript preparation. Data analysis was provided by Astra-Zeneca. All authors read and approved ... Agréus L, Jab-lonowski H, Tafalla M: Consultation rates and characteristics of gastroesophageal reflux disease in primary care: a European observational study. Eur J Gen Pract 2009 in press.16. ... (AstraZeneca study code: D9612L00114) was a multinational, observational programme that was con-ducted as a series of parallel, locally managed studies at134 primary care sites across six European...
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Báo cáo hóa học: " Impact of g-chain cytokines on EBV-specific T cell cultures" doc
... Natl Acad Sci USA 2009,106:17469-17474.9. Kaneko S, Mastaglio S, Bondanza A, Ponzoni M, Sanvito F, Aldrighetti L,Radrizzani M, La Seta-Catamancio S, Provasi E, Mondino A, Nagasawa T,Fleischhauer ... 105)werewashedwithphosphate-buffered saline (PBS; Sigma-Aldrich) and re-suspended in 50 μl of staining solution (PBS, 3% FBSand 0,1% NaN3) containing an optimal concentration of antibody. After a 20-minute incubation in ice, ... resulting in a better therapeuti c activity. In thisregard, the eradication of large established melanomas(approximately 50 mm2tumor area) was achieved by the infusion of as littl e as 5 ×...
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báo cáo hóa học: " Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy" ppt
... andperformed the statistical analysis. HTA conceived of the study, andparticipated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.Competing ... for Laboratory AnimalResearch (Guide for the Care and Use of Laboratory Ani-mals) in accordance with the ARVO Statement for the “Use of Animals in Ophthalmic and Vision Research” andwere approved ... microglia at vascular tufts at P1 7. Vascular tufts and other vessels (lectin staining, red) are located at the border of the vascularized and the avascular central zone in the superficial layer (s)....
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báo cáo hóa học: " Impact of a child with congenital anomalies on parents (ICCAP) questionnaire; a psychometric analysis" pptx
... clinical significance. Fur-ther data collection and analysis of data are, however, part of ongoing investigation in our institute.Conclusion The ICCAP is a reliable and valid instrument for clinicalpractice. ... interpretation of the data and drafted the manuscript. MD and HJD con-tributed to the statistical analysis, the interpretation of the data and helped to draft the manuscript. HMK and DTparticipated in the ... explanations present them-selves. On the one hand, parents may have gained betterunderstanding of what to expect in the future. On the other hand, the acute severity of disease and the child'sdiscomfort...
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báo cáo hóa học: " Impact of schizophrenia and schizophrenia treatment-related adverse events on quality of life: direct utility elicitation" pot
... quality of life and relapse and EPS the greatest impact on quality of life, indicating as clear anunderstanding by patients of the health states and theirimpact on quality of life as by laypersons. ... JL: Pharmacoeconomic evaluations of clozapine in treatment resistant schizophrenia and risperidone in chronic schizophrenia. Ottawa (ON) : Canadian CoordinatingOffice for Health Technology Assessment ... ability of a patient experiencing the disease toadapt to their health state [8,24]. Other research indicatesthat general population respondents focus more on the negative aspects of a health state...
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báo cáo hóa học: "Impact of chronic Immune Thrombocytopenic Purpura (ITP) on health-related quality of life: a conceptual model starting with the patient perspective" potx
... Administra-tion (FDA) and the European Agency for the Evaluation of Medicinal Products (EMEA) have emphasized the value of PRO measures in identifying and quantifying the impact of a disease ... that might not have been available on anindividual basis, it may also lead to overemphasis of the opinions of the groups' participants. For this reason, it iscritical to the success of a ... sub-categoriesincluded in each of the primary conceptual categories. The table indicates whether the sub-category was mentionedduring each of the focus groups and provides the number(and percentage) of patients...
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báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc
... performed the statistical analy-sis, and drafted the manuscript. AC participated in the study design and coordination. TL participated in the analyses of the ovarian ascites fluid. SA participated in ... interpretation of data, and critically revised the manuscript. PO participated in design, coordination, anddata interpretation and drafted the manuscript. Allauthors read and approved the final manuscript.AcknowledgementsWe ... into the peritoneum of a woman with advanced and recurrentovarian carcinoma. Following several infusions, a com-plete resolution of ascites was shown (Case report in prep-aration).ConclusionOn...
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Báo cáo hóa học: " Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies" doc
... 175:4745-4753.39. Ino K, Yamamoto E, Shibata K, Kajiyama H, Yoshida N, Terauchi M, Nawa A, Nagasaka T, Takikawa O, Kikkawa F: Inverse correlation between tumoralindoleamine 2,3-dioxygenase expression and ... results of statistical comparisons among baseline and post-treatment samples and between the two study groups have been detailed in the main text.Bonanno et al. Journal of Translational Medicine 2010, ... cells,thus contributing to leukemia eradication [55,56]. Theseconsiderations add to the knowledge that pegfilgrastimhasadvantagesoverfilgrastimintermsofpatientcom-pliance, ease of administration and...
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Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... blocks,using the RNA STAT-60TM Total RNA/mRNA isolationreagent, according to the manufacture’s instructions. The RNA was treated by RNAse-free DNAse I t o eliminateany contaminating DNA. Total cDNA ... conducted the study and conceived of the study, participated in design, coordination, data interpretation, performed the statistical analysis,and drafted the manuscript. AH - conceived of the study, ... growth,invasion, and metastatic activity), and by the ability totreat bladder tumors intravesically, the same way humanbladders are clinically treated. Therefore we evaluated the feasibility of intravesical...
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