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báo cáo hóa học: "Rasch analysis of the Multiple Sclerosis Impact Scale (MSIS-29)" pot

báo cáo hóa học:

báo cáo hóa học: "Rasch analysis of the Multiple Sclerosis Impact Scale (MSIS-29)" pot

... Disability Status Scale (EDSS) [10], Multiple Sclerosis Quality of Life (MSQOL-54) [11], the Multiple Sclerosis Quality of Life Inventory (MSQLI) [12], the Functional Assessment of Multiple Sclerosis ... increasing use of the MSIS-29 in research inmany parts of the world further analysis of the scale& apos;s psy-chometric properties needs to be undertaken. The aim of this study was to use Rasch analysis ... this is the first study to system-atically assess all aspects of the scale using Rasch analysis. Overall support was established for the psychometricproperties of the individual scales of the MSIS-29...
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báo cáo hóa học:

báo cáo hóa học:" Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells" potx

... the double treatment, showing an increase of the G1 peack at low dose BPA (30 μM) and an increase of the G2-M fraction of cells at the highest concentration of BPA (100 μM). Differently, in the ... health because of the high potential for exposure of humans to these phenolsand their demonstrated animal toxicity. Recently, atten-tion has focused on the carcinogenic adverse effects of BPA. Thus, ... on the other side we have to keep in mind that these effects mightalso be elicited in normal cells in the different compart-ments of the human body and thus might contribute to the toxicity of...
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Báo cáo hóa học:

Báo cáo hóa học: " Kinematic analysis of the daily activity of drinking from a glass in a population with cervical spinal cord injury" potx

... rotations of the forearm.In each recording, a complete cycle of the drinkingtask was identified. The beginning of the cycle was the onset o f displacement of the marker on the head of the third ... contributed to the concept,software development, design and acquisition of the data. MSM contributedto the analysis and acquisition of the data. AAE contributed to the analysis and acquisition of the ... the line that joined bothepicondyles in the lateral direction. In the hand, the ori-gin was at the midpoint between radial and ulnar styloidofthewrist,theY-axiswasthelinejoiningtheheadofthe...
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Tài liệu Báo cáo khoa học: Quantitative analysis of the experimental O–J–I–P chlorophyll fluorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier doc

Tài liệu Báo cáo khoa học: Quantitative analysis of the experimental O–J–I–P chlorophyll fluorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier doc

... amplitudes and rate constants of the two other phases. The above should be gov-erned by the balance between the rate of reductionand oxidation of the acceptor side of PSII by the avail-able electron ... half-time of the J–I phase were bothdecreased with DCMU, demonstrating that the J–I riseis not directly related to the reduction of the PQ pool.A further analysis of the influence of PQ reductionon ... correspond to the end of the J–I phase [8,28,29]. It is likely that the emergence of a peak for I in the FI curves depends on the relative amplitude and rate constant of the J–Iphase compared to the amplitudes...
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Tài liệu Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation ppt

Tài liệu Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation ppt

... connected to the DEC1 E-boxes(Fig. 2), while deletion of the Orange domain ( DEC1DOr-ange) had no effect on the suppressive activity, indicating the importance of t he bHLH region of DEC1. The HXXXXXXXR ... conclude that the basic region, p artic-ularly the conserved A rg65, but not His57, is essential for the suppressive activity of DEC1.Determination of the binding domain of DEC1 to BMAL1 The interaction ... network of the circadian clock system[11,12,14]. In fact, the circadian rhythms of Dec1 and Dec2expression have been shown to be completely disrupted in the SCN a nd some o ther tissues of Clock/Clock...
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Tài liệu Báo cáo khoa học: Fluorescence analysis of the Hansenula polymorpha peroxisomal targeting signal-1 receptor, Pex5p pdf

Tài liệu Báo cáo khoa học: Fluorescence analysis of the Hansenula polymorpha peroxisomal targeting signal-1 receptor, Pex5p pdf

... peptideconjugation. The three-dimensional model of the TPRdomain of HpPex5p complexed with L2 peptide confirmsthis hypothesis and shows that Trp453 is the chromophorelocated closest to the dansyl of the bound ... residues in the C-terminus of HpPex5p to the dansyl cap in the PTS1peptides, the distance between the dansyl cap in L2 and the three tryptophan residues in the model were measured. The values ... exposure of the Trp chromophores to the solvent, the differences in these values at the two pH values,most likely reflect a pH-related conformational change of the protein. Lowering the pH to...
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Báo cáo khoa học: Structure analysis of the flavoredoxin from Desulfovibrio vulgaris Miyazaki F reveals key residues that discriminate the functions and properties of the flavin reductase family pdf

Báo cáo khoa học: Structure analysis of the flavoredoxin from Desulfovibrio vulgaris Miyazaki F reveals key residues that discriminate the functions and properties of the flavin reductase family pdf

... of the structure of NADP+-bound FeRrevealed that the nicotinamide moiety of NADP+faces the re-side of the isoalloxazine ring, and that the 2¢-P-AMP moiety is held in the groove between the ... direction along the b10 of the other mono-mer, forming an anti-parallel intermolecular b sheet(Fig. 2A). The subsequent residues of the loop (Ala7–Pro13) turn into the interior of the dimer interface,and ... linearregression analysis of the logarithms of the concentrationratios for oxidized and reduced forms of the mediatorversus that of recombinant flavoredoxin.Reduction titration of flavoredoxin by NAD(P)HThe...
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Báo cáo khoa học: Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, a4 and the mammalian ortholog of yeast Tip41 (TIPRL) ppt

Báo cáo khoa học: Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, a4 and the mammalian ortholog of yeast Tip41 (TIPRL) ppt

... proteins. The 3D arrangement of the binding sitesfor TIPRL and a4 on the surface of PP2Ac shows thatthey are in close proximity, but not overlapping, whichallows the assembly of the TIPRL:PP2Ac:a4 ... indicates the elution positions of molecular mass markers are shownabove the panels. The profiles of the three proteins overlap over a region that coincides with the expected molecular mass of the ... Fig. 7. The interaction of PP2Ac with the regulatory B sub-unit requires the extreme C-terminal region of the cat-alytic subunit [29] and the interaction site for TIPRLwas mapped to the C-terminal...
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Báo cáo khoa học: Expression analysis of the nucleocytoplasmic lectin ‘Orysata’ from rice in Pichia pastoris ppt

Báo cáo khoa học: Expression analysis of the nucleocytoplasmic lectin ‘Orysata’ from rice in Pichia pastoris ppt

... [16,17]. The uncleaved part of the a-mating sequence at the N-ter-minus as well as the histidine tag at the C-terminus of the recombinant lectin apparently do not influence the biological activity of ... overall orientation of the cavities. (C), (F), (I) Ribbon diagrams at the top of the Man-binding lectins show-ing the overall topography of the carbohydrate-binding sites of Orysata (C), Calsepa ... strain X-33 with the addition of asignal sequence for secretion of the recombinant pro-tein into the medium. Approximately 12 mg of the recombinant lectin was purified from the medium of a1 L culture...
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Báo cáo khoa học: Functional analysis of the aglycone-binding site of the maize b-glucosidase Zm-p60.1 pot

Báo cáo khoa học: Functional analysis of the aglycone-binding site of the maize b-glucosidase Zm-p60.1 pot

... introducingfeatures of the consensus motif into the Zm-p60.1scaffold, an analysis of structural and catalytic prop-erties of the mutants, and simulations of the sub-strate–enzyme interactions of the wild-type ... F200Kand P2. Furthermore, the F193A and W373K muta-tions do not result in any change in the thermostability of the enzyme (Table S2), and thermal unfolding of the wild-type and both the F193A and ... cleavage and the roles of the catalyticpair, our knowledge of the molecular determinants of aglycone specificity in b-glucosidases remains limited.Elucidation of the aglycone specificity of b-glucosidasesis...
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