... TXA2 has been implicated as a mediator of a number of vascular disorders including thrombosis,unstable angina, myocardial infarction, pregnancy-inducedhypertension, bronchial asthma and glomerulonephritis[1,29,29,30]. ... region.Thromboxane (TX) A 2, generated through the sequentialmetabolism of arachidonic acid by cyclooxygenases 1/2and TXA2synthase, acts as a potent agonist of plateletactivation and aggregation and ... 5¢-dTGACTGATCCCTCAGGG-3¢ ()27 to )11, Exon 2); Kin60: 5¢-dCGAGGCCGCAGAGGAAGGTGA-3¢ (+211 to +191, Exon 2); Kin129:5¢-dCCCTCGCCCCACCCTCGG-3¢ ()196 to )180, Exon1); Kin130: 5¢-dGTTCAGTGGCACGATCTT-3¢...