... constitutes the final steps in the cel-lular life cycle of PV, appears to be linked to RNA synthesis[6] at the interface of membranous structures in the cyto-plasm of infected cells [153]. To start, ... between the SabinOPV strains and closely related viruses has come into the limelight. Indeed the propensity of OPV strains to recom-bine in recipients of the vaccine has been documented in numerous ... vaccine, the Sabin polio vaccine,was announced. With the introduction of effective vac-cines, the incidence of poliomyelitis rapidly declined.Indeed, in the United States, the last case of...