Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf
Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf
... ADAM 10 expression in SACC-LM cells To investigate whether ADAM 10 expression was essen-tial for the metastatic capability of SACC-LM cells, stable ADAM 10 RNAi transfected cells (SACC- ADAM1 0-RNAi) ... supportingtheroleofADAM10incellgrowthinSACC-LMcells(Figure 5 C). In addition, the affect of gene silencing of ADAM 10 on the cell migration ability of SACC-LM cells was also investigated by transwell ... designed using the software siRNA Target Designer (Promega, Madison,WI, USA). The preparation of the RNAi vector expres-sing the human ADAM 10 short hairpin RNA (shRNA)was performed using the pSuper...
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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf
... overall survival of treatedanimals (Figure 6D). These results confirm the anti-tumoractivity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans.DiscussionOur ... of complement; (1) In the presence of Alemtuzumab and heat inacti-vated sera, the majority of VLC are viable Annexin V (-) and PI (-) cells. In contrast, in the presence of Alemtuzumab and ... characterization of VLC, ascites associated cells were concentrated by centrifugation and then red blood cells were lysed using ACK buffer (lonza, Walkersville,MD. Host cells were then isolated using a...
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báo cáo hóa học: " Measuring adolescents'''' HRQoL via self reports and parent proxy reports: an evaluation of the psychometric " docx
... compare the internal consistency of item responses, factorial validity and invariance and the convergent and known-groups validity of the child-reportversion and the parent-report version of the ... analyses and wrote the man-uscript. BK and URS were the principal investigators of the study; they designed the study's concept and supervised the writing of the manuscript. UE assisted in the ... reported in the tables and in the text refers to weighted data and thus mightdeviate from the number of cases reported in the formerdescription of the sample.Health and Quality of Life Outcomes...
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báo cáo hóa học: " Measuring adolescents'''' HRQoL via self reports and parent proxy reports: an evaluation of the psychometric properties of both versions of the KINDL-R instrument" pdf
... cases. In 82.8% of cases, the proxy was the mother and in 11.4% it was the father. The mean age of mothers was 41.9 years and the mean age of fathers was44.9 years. The real household income ... compare the internal consistency of item responses, factorial validity and invariance and the convergent and known-groups validity of the child-reportversion and the parent-report version of the ... assess the HRQoL of children and adolescents.Several reviews and studies have examined the agreementbetween mental health and well-being reports made by parents and those made by the children themselves...
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báo cáo hóa học:" Caveolin-1 enhances resveratrol-mediated cytotoxicity and transport in a hepatocellular carcinoma model" docx
... effects of RES on the growth of serum-stimulated HepG2 cells. As shown in Table 1 and 2 and Figure 1A and Figure 1B, the MTT assay indicates that RESinhibits significantly the growth of serum-stimulatedHepG2 ... of CAV1. A solution of 228 mg (1.0 mmol) of RES in 10 mL of acetone was added into a mixture of 1 g of K2CO3 and 10 ml acetone in N2 atmosphere, 270 mg (1.0 mmol) of DAN in 10 mL of acetone added ... work and helped with the interpretation of the data, WYF, AW, EW and DFS supervised all the work and wrote the paper together with HLY and MFM. Allauthors read and approved the final manuscript.AcknowledgementsThis...
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báo cáo hóa học:" Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells" pdf
... in the design of the study and revised and drafted the manuscript. MC participated instudy design and coordination and revised and drafted the manuscript. AM participated in the design of the ... study and revised and drafted the manuscript. IDD participatedin the design of the study and revised and drafted the manuscript. WMK participated in study design and coor-dination and revised and ... healthydonors. All of the clinical materials were obtained with the patient's consent and approval by the local ethicscommittee.Constructing the AAV/IE1 genome and generation of virus stocks The AAV/IE1...
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báo cáo hóa học:" CTLA4 blockade increases Th17 cells in patients with metastatic melanoma" pdf
... transport, and the number of Th17 cells was determined by flow cytometry. Depicted are the plots of gated Th17 cells from patient NRA12. The left column is the baseline pre-dosing sample, and the right ... treatment received and the outcome after therapy. Two thirds of the patients had M1cmetastatic melanoma (visceral metastasis and/ or highLDH), and most of the remaining patients had either intransit ... inculture supernatants of activated whole PBMC and CD4-sorted cells (Figure 4A and 4B), as well as in the number of IL-17-producing cells determined by ICS, in bothwhole PBMC and CD4-sorted cells (Figure...
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Báo cáo hóa học: " Non-monotonic changes in clonogenic cell survival induced by disulphonated aluminum phthalocyanine photodynamic treatment in a human glioma cell line" pot
... concentra-tions of AlPcS2 (1 -10 μM) in HBSS at 37°C. After incuba-tion of cells in HBSS, both the absorption and fluorescence spectra (exc. 610 nm; em. 625-800 nm) of cells and supernatant before and ... and analyzed using the software provided by Opti-mas Corporation, USA.Cytoplasmic and nuclear localization of the sensitizerwas estimated by analyzing the images using area mor-phometry by ... helped to draft the manuscript. KM helped in the interpretation of the data on uptake and localization of phthalocyanine and drafting of the manuscript. VJ con-ceived the study and participated...
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Báo cáo hóa học: " Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats" pptx
... safety and effectiveness as well as a thorough under-standing of the underlying mechanism of actions. The use of an animal model of acute IS, therefore, is imperative toinvestigate the short and ... of CXCR4 and SDF-1α in BIA, ADMSC therapy also mark-edly increased the cellular expression of vWF that is amarker of endothelial cells. Importantly, ADMSC therapyalso increased the number of small ... and ApoptosisIn the present study, the mRNA expressions of IL-18,TLR-4, and PAI-1 were markedly upregulated in rats afteracute IS. In addition, the mRNA expressions of Bax and caspase 3 were...
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báo cáo hóa học: " Reduction in patient burdens with graphical computerized adaptive testing on the ADL scale: tool development and simulation" doc
... database, designed and performed the statistical analysis and wrote the man-uscript. HW and WW contributed to the development of the study design and advised about the performance of the statistical ... StrokeImpact Scale and others. The psychometric properties of these scales are often investigated using classic test theorywhere a raw score is generally used to describe a patient'slevel of ADL function. ... contributed to the revision of manuscript. The analysis and results were discussed with the five authors together. HW, WW, RC and WC revised the manuscript critically several times. WW advised the CAT...
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