Báo cáo hóa học: " Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance" pptx
Báo cáo hóa học: " Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance" pptx
... 8:101http://www.translational-medicine.com/content/8/1/101Page 11 of 11RESEARC H Open Access Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significanceChun-Wei ... on Cancer 2009, 1796:11-18.doi:10.1186/1479-5876-8-101Cite this article as: Peng et al.: Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory ... 8:101http://www.translational-medicine.com/content/8/1/101Page 9 of 11Figure 1 Co-evolution of tumor cells and their microenvironment in cancer invasions. Both of tumor cells and their microenvironment areinvolved in cancer invasions. Invasion...
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báo cáo hóa học:" Survivin gene levels in the peripheral blood of patients with gastric cancer independently predict survival" doc
... management of thesepatients.Background Gastric cancer represents the fourth most common cancer and second leading cause of cancer- related death world-wide. The estimated current incidence of gastric ... XiaoHB, Gao E: Detection of survivin-expressing circulating cancer cells (CCCs) in peripheral blood of patients with gastric and colorectal cancer reveals high risks of relapse. Ann Surg Oncol2008, ... marker of circulating tumor cells(CTC) in different kind of cancer, but the available dataare scarce [18,19]. In a series of 26 gastric cancer patients,Survivin mRNA (as measured by means of ELISA-basedqrtPCR)...
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Báo cáo hóa học: " Oxidative stress in NSC-741909-induced apoptosis of cancer cells" potx
... Structures of oncrasin-1 and NSC-741909.Additional file 2 NSC-741909-induced apoptosis and ROS in the pres-ence or absence of siRNA of 5-, 12-, and 15-Lox. Control siRNA and 5-, 12- and 15-Lox ... Details1Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China, 2Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson ... Anderson Cancer Center, Houston, Texas 77030, USA, 3Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA and 4Department of Pathology,...
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báo cáo hóa học:" BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?" ppt
... breast and ovarian cancer but also to prostate cancer, colon cancer, pancreatic cancer and male breast cancer [3]. Only 5-10% of all these can-cers are actually related to one of several familial ... recognition of DNA DSBs, BRCA1 is phosphorylated and leads to activa-tion of the DSB repair by HR [22]. HR is an error-free path-way and operates the repair of DSBs in the late S and G2phases of the ... PARP1binds to the sites of damage at the single strand and cata-lyzes the synthesis and subsequent transfer of chains of poly-(ADP)-ribose (PAR) to carboxylic groups of severalproteins, including...
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báo cáo hóa học:" PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study" docx
... role of oestrogen receptor α and β subtypes in clinical breast cancer. Int J Cancer 2000, 89:209-212.19. Elston W, Ellis IO: Pathological prognostic factors in breast cancer. The value of histologic ... over-expression and increased mortality may be just a conse-quence of tumour progression translated as theTable 2: Distribution of demographic, clinical, and pathological variables of breast cancer ... estimates of breast cancer patients overexpressing PAR1: those with and without metastasesFigure 2Kaplan-Meier survival estimates of breast cancer patients overexpressing PAR1: those with and without...
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Báo cáo hóa học: "Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy" pdf
... human cancers and can predictresponsiveness of brea st cancer to chemotherapy and radiation therapy based on the expression pattern of ISGs.In this study, we identified by transcriptional profilingtwo ... Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda,Maryland, USA.5Department of Surgery, University of Verona Medical School,Verona, ... possibly a widespreadphenomenon among cancers; 2) the activation of ISGs isdue to two independent taxonomies of cancer cells and not to the host’ s reaction to the cancer a s it is wasobserved in...
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Báo cáo hóa học: " Abstract Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor." ppt
... survival and quality of life tobecome integrated into the standard of care regime[5,52-54].The number of slots open for patient accrual to theimmunotherapy protocols contained in our list of o ... USA.3Department of Neurosurgery and Jonsson Comprehensive Cancer Center,David Geffen School of Medicine, University of California, Los Angeles, LosAngeles, CA 90049, USA.Authors’ contributionsMJH and ... identifies clinically relevant subtypes of glioblastomacharacterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17:98-110.3. Huse JT, Holland EC: Targeting brain cancer: ...
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Báo cáo hóa học: " Exploring the molecular mechanisms underlying the potentiation of exogenous growth hormone on alcohol-induced fatty liver diseases in mice" ppt
... the surface of target cells and induces the association of GHR with Janus kinase(JAK)-2 to initiate tyrosine phosphorylation of GHR and JAK2. Ph osphorylation of GHR and JAK2 consequentlyactivates ... Natural Science Foundation of China (No. 20635002).Authors’ contributionsGuarantor of integrity of entire study, Y.Q., and Y.P.T.; study concepts and design: Y. Q., and Y.P.T.; data acquisition/analysis/interpretation: ... adipocyte adiponectin and adipoR2expression via the JAK2 and p38 MAPK pathways, and raise serum HMW adiponectin, the most active adipo-nectin isoform in the regulation of insulin and bloodglucose...
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Báo cáo hóa học: " Cathepsin B: a potential prognostic marker for inflammatory breast cancer" ppt
... decreased trafficking of CTSBto caveolae on the surface of these cells and decreaseddegradation of ECM proteins and cellular invasion [25].Although the role of cav-1 in breast cancer is contradic-tory, ... expres-sion and the metastasis of carcinoma cells to lymph nodeshas previously been reported in breast [30], prostate [31] and gastric [32] cancers. Overexpression of CTSB in breast cancer has ... AnalysisThedatawereanalyzedusingSPSSsoftwareversion16.0. Differences were evaluated by Student’st-testandFisher’s exact test. Immunohistochemical scores of 0 and + were considered negative and scores of ++ and +++ were...
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báo cáo hóa học: "Investigating the missing data mechanism in quality of life outcomes: a comparison of approaches" pdf
... Peter M Fayers1,2 and Craig R Ramsay3Address: 1Section of Population Health, University of Aberdeen, UK, 2Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian ... procedures. The variety of datasets allowed the proce-dures to be investigated for different proportions of miss-ing data and for different missing data patterns. Health and Quality of Life Outcomes ... period of intermittent miss-ingness is followed by monotone missingness. The threemechanisms of missing data are missing completely atrandom (MCAR), missing at random (MAR) and missingnot at random...
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