Báo cáo hóa học: " Copy number and gene expression differences between African American and Caucasian American prostate cancer" docx

... of African American and Caucasian American patients and tumors utilized for BAC-based DNA copy number analysis and gene expression profiling African American( n = 20) Caucasian American( n ... distribution, and reproduction inany medium, provided the original work is properly cited.Research Copy number and gene expression differences between African American and Caucasian American prostate ... gene expression and DNA copy number that are specific to African American and Caucasian prostate cancer and may be related to underlying differences in immune response.Background African Americans...

báo cáo hóa học:" Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood " pot

... high on days 3 and 10 (mid-way between injections) and much lower ondays 6, 13 and 42 (just before subsequent injections)(Table 3, Figure 1). The number of genes with altered expression was ... CD:Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype1. Gastroenterology 2006, 131:470-477.Additional file 1 List of genes with significant ... weeks. Genes induced by the treatment fall intothree classes, genes that are up regulated throughout thetreatment, immediate expressed genes with only transient expression, and late genes in...

Báo cáo hóa học: " Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity" ppt

... titativePCR(qPCR)andELISAwereusedtoconfirmthemicroarray results for relative gene expression between control and IRAK4-deficient monocytes, and to establishthe absolute expression of mRNA and protein ... (Invivogen). Based on pre-vious studies, LPS-induced gene transcription in mono-cytes peaked (with respect to the number of genes and the magnitude of gene expression) after 4 hr of stimula-tion, at ... more, these data demonstrated that the observed gene expression is regulated and the reciprocal relation-ships between certain genes (e.g., over -expression ofZFP36L2 & IL13RA1 with repression...

Tài liệu Báo cáo khoa học: Hsp105b upregulates hsp70 gene expression through signal transducer and activator of transcription-3 pdf

... hsp70 and hsp90 promoters [21]. As we showed, in this study, thatSTAT3 directly bound to the region between )206 and )187 bp of the hsp70 promoter and enhanced the expression of the hsp70 gene ... Hsp105b-induced expression of the hsp70 gene. STAT3, but not HSF1, binds to the region between )206 and )187 bp of the hsp70promoterNext, we investigated protein binding to the region between )206 and ... for the human hsp70 gene between )272 and )13 (forward, 5¢-CCA TGG AGACCA ACA CCC T-3¢; reverse, 5¢-CCC TGG GCT TTTATA AGT CGT-3¢), or the human hsp70 gene between )1860 and ) 656 (forward,...

Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx

... inducerof uPA gene expression [16].Decma-induced uPA gene expression isdependent on Erk activationWe and others have shown that activation of Erk playsan important role in uPA gene expression ... E-cadherin distribution, cell scattering and uPA expression. (A) T47D cells (a and b) and MCF7 cells(c and d) were treated for 4 h with control or Decma supernatant and immunostained with anti-E-cadherin ... Basel, Switzerland) and details will be pub-lished elsewhere.Plasmids and siRNAsConstruction of expression vectors for HA-tagged full-length mouse p46shc, p52shc, and p66shc and the introduct-ion...

Báo cáo khoa học: Glutamine stimulates the gene expression and processing of sterol regulatory element binding proteins, thereby increasing the expression of their target genes docx

... SREBP target gene, and that the transcription of SREBP-1a gene ispredominantly regulated by the general transcriptionfactor Sp1 [11,12]. We next compared the glutamine-induced gene expression ... in the induction ofSREBP-1a gene expression. When endogenous Sp1 expression was reduced to  20% of normal with gene- speciﬁc small interfering RNA (siRNA), the gene expression of SREBP-1a was ... of SREBP gene expression is not theinitial trigger for the glutamine effectsIf induction of the SREBP gene expression serves asthe initial trigger for the glutamine effects, the gene expression...

báo cáo hóa học:" Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model" doc

... latency,threshold and amplitude of electromyogram and number, thickness, circumference and area of myelinated nerve fib-ers derived from rabbits with and without facial nerveinjury and repair using ... contributionsHZ and TWY collected and analyzed data. KST interpreteddata and wrote the manuscript. CRS, JL and HH acquireddata. FZC analyzed and interpret data. YHA designed thestudy and approved ... enhancedNSCs differentiation and neurite outgrowth, but also pro-vided growth factor to promote endogenous regeneration and lessen degeneration.Peripheral nerve regeneration was evident with...

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báo cáo hóa học:" High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia" pot

... which distinguishes between ALL in infants and older children [8,9]. Recently, Balkhi and co-workerswere able to identify significant differences in the AMLproteome between cytogenetic groups of ... cancer a hypermethylation of the CpGisland of the σ gene was found that leads to gene silencing and absence of 14-3-3σ. The authors conclude, that theloss of σ expression contributes to malignant ... AL, DN, and JP carried out the 2D electrophoresis and all other experimental work. PS, ET, and WKH coor-dinated the laboratory work and helped to draft the man-uscript. All authors read and approved...

báo cáo hóa học:" Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs" pot

... activation and generation of CTLs. Activated and mature DCs results inantigen-specific immunity, while fully immature and inactivated DCs can induce inhibition of the immuneresponse and the generation ... with DCT and DCTI in 10 patients. Both vaccines (DCT and DCTI) were equivalent in eliciting CD8+T cell responses and there were no sta-tistically significant differences between DCT and DCTI ... fromthe American Type Culture Collection (ATCC) and main-tained in Iscove's Modified Dulbecco's Medium supple-mented with glutamine, and penicillin and streptomycin(100 IU/ml and 100...

báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

... popula-tion [6] and are able to generate non hematopoietic tis-sues including adipocytes, chondrocytes, osteocytes,myocytes [7,8] and cardiomyocites [9]. Angiogenesis and vascuologenesis are responsible ... pertaining to biologic products and human cells, tissues, and cellular and tissue-basedproducts provide an appropriate structure for ensuring thesafety and efficacy of the next generation of stem cell-based ... makesreference to and is in coherence with the 2004/23/ECdirective on donation, procurement and testing of humancells and tissues and with directive 2002/98/EC onhuman blood and blood components....

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