... par-tially due to the inhibition of renal tubular secretion of creatinine by acyclovir, and not entirely the result of decreased GFR. To the best of our kno wledge, the effect of acyclovir on the renal ... for 6 and 3 days, respectively, after seeding. Alltransepithelial transport studies were conducted on con-fluent cell monolayers.At the time of commencement of the transportexperiments, the ... Giacomini KM: Transporters involved in the elimination of drugs in the kidney: organic anion transporters andorganic cation transporters. J Pharm Sci 2001, 90:397-421.44. Grundemann D, Babin-Ebell...